2012
Relapsing and Remitting Severe Hypoglycemia due to a Monoclonal Anti-insulin Antibody Heralding a Case of Multiple Myeloma
Waldron-Lynch F, Inzucchi SE, Menard L, Tai N, Preston-Hurlburt P, Hui P, McClaskey J, Hagopian WA, Meffre E, Marks PW, Wen L, Herold KC. Relapsing and Remitting Severe Hypoglycemia due to a Monoclonal Anti-insulin Antibody Heralding a Case of Multiple Myeloma. The Journal Of Clinical Endocrinology & Metabolism 2012, 97: 4317-4323. PMID: 23074233, PMCID: PMC3513536, DOI: 10.1210/jc.2012-2388.Peer-Reviewed Original ResearchConceptsInsulin autoimmune syndromeAnti-insulin antibodiesMonoclonal anti-insulin antibodiesMultiple myelomaPathogenic antibodiesCases of MMSelf-reactive clonesPrimary multiple myelomaSynchronized courseHepatitis C.Autoimmune syndromeClinical courseSevere hypoglycemiaAntibody subtypesMonoclonal gammopathyPatientsAntibodiesNovel caseHypoglycemiaMyelomaAffinity maturationLongitudinal case historiesLaboratory investigationsTreatmentLow affinity
2005
Recurrent endometrial stromal tumors with smooth-muscle differentiation and a protracted clinical course
Hui P, Fedoriw G. Recurrent endometrial stromal tumors with smooth-muscle differentiation and a protracted clinical course. Nature Reviews Clinical Oncology 2005, 2: 588-593. PMID: 16270099, DOI: 10.1038/ncponc0340.Peer-Reviewed Original ResearchConceptsEndometrial stromal tumorsSmooth muscle differentiationStromal tumorsPhysical examinationHeavy vaginal bleedingInvestigations Physical examinationPartial wedge resectionAnterior uterine wallTotal abdominal hysterectomySignificant family historyUterine dilationAbdominal hysterectomyAbdominal myomectomyExploratory laparotomyVaginal bleedingAbdominal crampsWedge resectionClinical courseGravida 1Cervical osMedical historyGynecological problemsFamily historyWeeks durationUterine wall