Frequent KRAS mutation in complex mucinous epithelial lesions of the endometrium
Alomari A, Abi-Raad R, Buza N, Hui P. Frequent KRAS mutation in complex mucinous epithelial lesions of the endometrium. Modern Pathology 2013, 27: 675-680. PMID: 24186144, DOI: 10.1038/modpathol.2013.186.Peer-Reviewed Original ResearchConceptsPositive predictive valueMucinous lesionsKRAS mutationsMucinous changeMucinous adenocarcinomaEndometrial mucinous carcinomaHigh positive predictive valueComplex atypical hyperplasiaRisk stratification algorithmAtypical complex hyperplasiaImportant prognostic indicatorFrequent KRAS mutationsKRAS mutation analysisComplex hyperplasiaHysterectomy specimensClinical progressionEndometrial lesionsMucinous carcinomaAtypical hyperplasiaPrognostic indicatorMucinous differentiationEpithelial lesionsCurettage casesStratification algorithmPredictive valuePartial Hydatidiform Mole
Buza N, Hui P. Partial Hydatidiform Mole. International Journal Of Gynecological Pathology 2013, 32: 307-315. PMID: 23518914, DOI: 10.1097/pgp.0b013e3182626011.Peer-Reviewed Original ResearchConceptsVillous sizeVillous hydropsMorphologic featuresHigh positive predictive valueCases of PHMSignificant histologic overlapPositive predictive valuePopulations of villusPartial Hydatidiform MoleCistern formationRoutine workupGynecologic pathologistsVillus sizeDefinitive diagnosisHistologic diagnosisHistologic findingsAvailable hematoxylinHistologic overlapDNA genotypingHistologic parametersEosin slidesPredictive valueDiagnostic significanceChromosomal trisomiesTrophoblastic hyperplasia