2020
Lack of genetic homozygosity in prepubertal teratomas: divergent pathogenesis distinct from that of teratomas in adolescents
Snir OL, DeJoseph M, Wu X, Rottmann D, Wong S, Buza N, Hui P. Lack of genetic homozygosity in prepubertal teratomas: divergent pathogenesis distinct from that of teratomas in adolescents. Laboratory Investigation 2020, 100: 1447-1454. PMID: 32694569, DOI: 10.1038/s41374-020-0468-6.Peer-Reviewed Original ResearchConceptsOvarian teratomaPatient ageImmature teratomaTesticular teratomaMature teratomaSacrococcygeal teratomaMixed germ cell tumorGerm cell tumorsMature ovarian teratomaChildren 18 yearsDivergent pathogenesisGenetic zygosityPrepubertal teratomasCell tumorsGonadal teratomaTeratomaGenetic homozygosityNormal tissuesPatientsGerm cell developmentSacrococcygealAgeCell developmentDepartmental archivesGerm cells
2017
Frequent homozygosity in both mature and immature ovarian teratomas: a shared genetic basis of tumorigenesis
Snir OL, DeJoseph M, Wong S, Buza N, Hui P. Frequent homozygosity in both mature and immature ovarian teratomas: a shared genetic basis of tumorigenesis. Modern Pathology 2017, 30: 1467-1475. PMID: 28664933, DOI: 10.1038/modpathol.2017.66.Peer-Reviewed Original ResearchConceptsMixed germ cell tumorGerm cell tumorsPure immature teratomaImmature teratomaCell tumorsMature teratomaGenetic zygosityMixed ovarian germ cell tumorOvarian germ cell tumorsOvarian immature teratomaImmature ovarian teratomaDifferent pathogenetic pathwaysMature cystic teratomaImmature teratoma componentsDifferent biological behaviorTeratoma componentsRate of homozygosityCystic teratomaOvarian teratomaTumor recurrenceCommon cellular originPathogenetic pathwaysGrade 2TumorsTeratoma
2010
Nonepithelial Tumor of Ovary
Chhieng D, Hui P. Nonepithelial Tumor of Ovary. Current Clinical Pathology 2010, 173-191. DOI: 10.1007/978-1-60761-164-6_11.Peer-Reviewed Original ResearchEpithelial Neoplasms of Ovary
Chhieng D, Hui P. Epithelial Neoplasms of Ovary. Current Clinical Pathology 2010, 145-172. DOI: 10.1007/978-1-60761-164-6_10.Peer-Reviewed Original ResearchSurface epithelial tumorsGerm cell tumorsCell tumorsEpithelial tumorsOvarian neoplasmsPrimary ovarian neoplasmsSex cord tumorSex cord differentiationPrimary ovarian tumorsOvarian stromal cellsTransitional cell tumorsBreast primaryHistological subtypesOvarian tumorsClinical behaviorClinicopathological stagingEpithelial neoplasmsSecondary tumorsClear cellsTheca cellsGranulosa cellsCell originTumorsLeydig cellsStromal cells