2014
Egg Donor Pregnancy
Buza N, Hui P. Egg Donor Pregnancy. International Journal Of Gynecological Pathology 2014, 33: 507-510. PMID: 25083967, DOI: 10.1097/pgp.0b013e3182a1028b.Peer-Reviewed Original ResearchConceptsDonor pregnanciesMedical recordsClinical gestational ageFirst case reportPatients' medical recordsPositive nuclear stainingNormal staining patternVillous stromal cellsMaternal decidual tissuesDNA genotypingChorionic villous tissueGestational ageUnderwent dilationCase reportUterine contentsVillous tissueMorphologic featuresStromal cellsPregnancyStaining patternComplete hydatidiformPartial hydatidiformChorionic villiNuclear stainingMicroscopic evaluation
2013
Partial Hydatidiform Mole
Buza N, Hui P. Partial Hydatidiform Mole. International Journal Of Gynecological Pathology 2013, 32: 307-315. PMID: 23518914, DOI: 10.1097/pgp.0b013e3182626011.Peer-Reviewed Original ResearchConceptsVillous sizeVillous hydropsMorphologic featuresHigh positive predictive valueCases of PHMSignificant histologic overlapPositive predictive valuePopulations of villusPartial Hydatidiform MoleCistern formationRoutine workupGynecologic pathologistsVillus sizeDefinitive diagnosisHistologic diagnosisHistologic findingsAvailable hematoxylinHistologic overlapDNA genotypingHistologic parametersEosin slidesPredictive valueDiagnostic significanceChromosomal trisomiesTrophoblastic hyperplasiaCancerous ‘floater’: a lesson learned about tissue identity testing, endometrial cancer and microsatellite instability
Bossuyt V, Buza N, Ngo NT, Much MA, Asis MC, Schwartz PE, Hui P. Cancerous ‘floater’: a lesson learned about tissue identity testing, endometrial cancer and microsatellite instability. Modern Pathology 2013, 26: 1264-1269. PMID: 23558568, DOI: 10.1038/modpathol.2013.63.Peer-Reviewed Original ResearchConceptsEndometrial curettageBackground endometriumStaging surgeryEndometrial cancerEndometrial polypsEndometrioid adenocarcinomaEndometrial adenocarcinomaFurther workupPap smearSecretory endometriumDiagnostic workupEndometrial cellsDNA genotypingAdenocarcinoma tissuesMolecular testingMicrosatellite instabilityAllelic patternsAdenocarcinomaPatientsConfirmation of contaminationTissue fragmentsCurettageEndometriumWorkupMolecular pathologists
2008
Epithelioid trophoblastic tumor: comparative genomic hybridization and diagnostic DNA genotyping
Xu ML, Yang B, Carcangiu ML, Hui P. Epithelioid trophoblastic tumor: comparative genomic hybridization and diagnostic DNA genotyping. Modern Pathology 2008, 22: 232-238. PMID: 18820674, DOI: 10.1038/modpathol.2008.165.Peer-Reviewed Original ResearchMeSH KeywordsAdultCarcinoma, Squamous CellComparative Genomic HybridizationDiagnosis, DifferentialEndometrial NeoplasmsEpithelioid CellsFemaleGene Expression Regulation, NeoplasticGenetic TestingGenotypeGestational Trophoblastic DiseaseHumansItalyLung NeoplasmsMiddle AgedPregnancyUnited StatesUterine Cervical NeoplasmsConceptsEpithelioid trophoblastic tumorTrophoblastic tumorSquamous cell carcinomaUterine cervixComparative genomic hybridizationCommon squamous cell carcinomaChromosomal alterationsInvasive squamous cell carcinomaChorionic-type intermediate trophoblastGestational trophoblastic diseaseGenomic hybridizationDNA genotypingIntermediate trophoblastTrophoblastic diseaseAnatomic locationComparative genomic hybridization analysisTrophoblastic originTumorsGenomic hybridization analysisCervixNormal tissuesTrophoblastic natureConventional comparative genomic hybridizationCarcinomaChromosomal profileGenotypic Analysis of Hydatidiform Mole: An Accurate and Practical Method of Diagnosis
Bifulco C, Johnson C, Hao L, Kermalli H, Bell S, Hui P. Genotypic Analysis of Hydatidiform Mole: An Accurate and Practical Method of Diagnosis. The American Journal Of Surgical Pathology 2008, 32: 445-451. PMID: 18300805, DOI: 10.1097/pas.0b013e3181520034.Peer-Reviewed Original ResearchConceptsMolar pregnancyMaternal endometrial tissuesDaily clinical practiceDNA ploidy analysisDNA genotypingCases of HMUnstained paraffin sectionsHistologic featuresEndometrial tissueMorphologic mimicsClinical practiceMolar gestationHydatidiform MoleParaffin sectionsChorionic villiDiagnosisRoutine diagnosisPregnancyPloidy analysisGenotypic analysisGenotypingPaternal originPCR amplification systemGestationCasesPrimary or Secondary? Genotyping Confirmation of an Ovarian Primary Carcinoid Tumor
Dotto J, Mezzetti T, Hui P. Primary or Secondary? Genotyping Confirmation of an Ovarian Primary Carcinoid Tumor. International Journal Of Gynecological Pathology 2008, 27: 33-36. PMID: 18156971, DOI: 10.1097/pgp.0b13e318053df4.Peer-Reviewed Original ResearchConceptsPrimary carcinoid tumorCarcinoid tumorsGerm cell originCell originInsular carcinoid tumorPure histological typePrimary ovarian tumorsSignificant diagnostic challengeExtraovarian tumorMetastatic carcinoidLymphovascular invasionHistological typeOvarian tumorsMetastatic tumorsClinical managementDiagnostic challengeTeratomatous componentsGastrointestinal tractTumorsAdditional studiesDNA genotypingCarcinoidsPrognosisTractWomen