The lifelong maintenance of mesencephalic dopaminergic neurons by Nurr1 and engrailed
Alavian KN, Jeddi S, Naghipour SI, Nabili P, Licznerski P, Tierney TS. The lifelong maintenance of mesencephalic dopaminergic neurons by Nurr1 and engrailed. Journal Of Biomedical Science 2014, 21: 27. PMID: 24685177, PMCID: PMC3998737, DOI: 10.1186/1423-0127-21-27.Peer-Reviewed Original ResearchConceptsMesencephalic dopaminergic neuronsDopaminergic neuronsParkinson's diseaseSubstantia nigra pars compactaMidbrain dopaminergic neuronsLong-term survivalPars compactaSet of neuronsPathological hallmarkNormal physiological functionNeurotransmitter identityNeurophysiological functionsNeuronsDiseaseLifelong maintenanceCurrent reviewTranscription factorsNurr1DegenerationPhysiological functionsReviewFactorsSpecific vulnerabilitiesMidbrainCompacta