The Receptor for Advanced Glycation End Products (RAGE) Affects T Cell Differentiation in OVA Induced Asthma
Akirav EM, Henegariu O, Preston-Hurlburt P, Schmidt AM, Clynes R, Herold KC. The Receptor for Advanced Glycation End Products (RAGE) Affects T Cell Differentiation in OVA Induced Asthma. PLOS ONE 2014, 9: e95678. PMID: 24759895, PMCID: PMC3997417, DOI: 10.1371/journal.pone.0095678.Peer-Reviewed Original ResearchConceptsAdaptive immune responsesT cell responsesEffects of RAGEGlycation end productsT cell activationT cellsImmune responseWT miceCellular infiltrationCell activationCell responsesBronchial alveolar lavage fluidAdvanced glycation end productsMediastinal lymph nodesT cell infiltrationIL-5 productionOT-II miceRAGE-deficient miceT cell subsetsAlveolar lavage fluidMultiplex bead analysisRole of RAGET cell proliferationDeficient T cellsT cell differentiation