On the complexity of self
Rudensky A, Rath S, Preston-Hurlburt P, Murphy D, Janeway C. On the complexity of self. Nature 1991, 353: 660-662. PMID: 1656278, DOI: 10.1038/353660a0.Peer-Reviewed Original ResearchConceptsMHC class II moleculesClass II moleculesSelf peptidesT cellsY-AeSelf MHC class II moleculesCD4 T cellsMajor histocompatibility complex moleculesMHC class IIMHC class II complexesHistocompatibility complex moleculesClass II complexesIntrathymic selectionSelf antigensIntrathymic developmentNovel MHCClass II