2014
The impact of buprenorphine/naloxone treatment on HIV risk behaviors among HIV-infected, opioid-dependent patients
Edelman EJ, Chantarat T, Caffrey S, Chaudhry A, O’Connor P, Weiss L, Fiellin DA, Fiellin LE. The impact of buprenorphine/naloxone treatment on HIV risk behaviors among HIV-infected, opioid-dependent patients. Drug And Alcohol Dependence 2014, 139: 79-85. PMID: 24726429, PMCID: PMC4029496, DOI: 10.1016/j.drugalcdep.2014.03.006.Peer-Reviewed Original ResearchConceptsBuprenorphine/naloxone treatmentOpioid-dependent patientsHIV risk behaviorsBuprenorphine/naloxoneNon-condom useNaloxone treatmentRisk behaviorsTreatment initiationViral loadHIV-1 RNA viral loadCocaine/amphetaminesTime-updated variablesRNA viral loadMajor risk factorOpioid-dependent populationsCochran-Armitage trend testSexual risk behaviorsOlder patientsHIV infectionOpioid dependenceRisk factorsHeroin useHIVPatientsTargeted interventions
2000
Naltrexone-Induced Nausea in Patients Treated for Alcohol Dependence: Clinical Predictors and Evidence for Opioid-Mediated Effects
O'Malley S, Krishnan-Sarin S, Farren C, O'Connor P. Naltrexone-Induced Nausea in Patients Treated for Alcohol Dependence: Clinical Predictors and Evidence for Opioid-Mediated Effects. Journal Of Clinical Psychopharmacology 2000, 20: 69-76. PMID: 10653211, DOI: 10.1097/00004714-200002000-00012.Peer-Reviewed Original ResearchConceptsRisk of nauseaEndogenous opioid systemIntensity of drinkingSevere nauseaOpioid systemAlcohol useLight drinkersMost alcoholic patientsWeeks of naltrexoneOpen-label trialLong-term alcohol usePoor medication compliancePretreatment patient characteristicsLogistic regression analysisAlcohol-dependent subjectsDays of abstinenceDuration of abstinenceSignificant nauseaPatient characteristicsClinical predictorsEndogenous opioidsMedication complianceAlcoholic patientsNaltrexone doseRisk factors
1998
Risk factors for and knowledge of Mycobacterium tuberculosis infection among drug users in substance abuse treatment
Durante AJ, Selwyn PA, O'Connor PG. Risk factors for and knowledge of Mycobacterium tuberculosis infection among drug users in substance abuse treatment. Addiction 1998, 93: 1393-1401. PMID: 9926545, DOI: 10.1046/j.1360-0443.1998.939139310.x.Peer-Reviewed Original ResearchConceptsMycobacterium tuberculosis infectionTB knowledgeTuberculosis infectionDrug treatment programsRisk factorsDrug usersPositive TB skin testsTreatment programTB skin testTB risk factorsM. tuberculosis infectionTuberculin skin testingLow TB incidenceNeedles/syringesNon-white raceIncidence of infectionDrug treatment facilitiesPrevalence of infectionSubstance abuse treatmentSubsample of clientsPreventive therapyTB controlSkin testingTB incidenceInfected subjects
1994
HIV infection and cocaine use in methadone maintained and untreated intravenous drug users
Meandzija B, O'Connor P, Fitzgerald B, Rounsaville B, Kosten T. HIV infection and cocaine use in methadone maintained and untreated intravenous drug users. Drug And Alcohol Dependence 1994, 36: 109-113. PMID: 7851277, DOI: 10.1016/0376-8716(94)90092-2.Peer-Reviewed Original ResearchConceptsIntravenous drug usersMethadone maintenance treatmentMethadone maintenance programHIV infectionCocaine useMore cocaine useMaintenance treatmentRisk factorsDrug usersMethadone maintenance treatment groupHuman immunodeficiency virus (HIV) transmissionAfrican AmericansMaintenance treatment groupNon-infected subjectsInjection frequencyHIV-negativeHIV testingDrug injectionStratified analysisTreatment groupsTotal cocaineHIVRisk behaviorsGreater riskInfection