2011
Hepatic Safety and Lack of Antiretroviral Interactions With Buprenorphine/Naloxone in HIV-Infected Opioid-Dependent Patients
Vergara-Rodriguez P, Tozzi MJ, Botsko M, Nandi V, Altice F, Egan JE, O'Connor PG, Sullivan LE, Fiellin DA. Hepatic Safety and Lack of Antiretroviral Interactions With Buprenorphine/Naloxone in HIV-Infected Opioid-Dependent Patients. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2011, 56: s62-s67. PMID: 21317596, DOI: 10.1097/qai.0b013e31820a820f.Peer-Reviewed Original ResearchConceptsBuprenorphine/naloxoneOpioid-dependent patientsMedian aspartate aminotransferasePharmacodynamic interactionsAspartate aminotransferaseBup/ALT valuesAlanine aminotransferaseBUP/NXOpioid-dependent HIVProspective cohort studyHepatic safetyHepatitis CCohort studyHepatic toxicityHIVPatientsAtazanavirNaloxonePrior reportsExposure measuresSignificant decreaseAminotransferaseSignificant changesTreatment
2006
Are Commonly Ordered Lab Tests Useful Screens for Alcohol Disorders in Older Male Veterans Receiving Primary Care?
Reid MC, Guo Z, Van Ness PH, O'Connor PG, Concato J. Are Commonly Ordered Lab Tests Useful Screens for Alcohol Disorders in Older Male Veterans Receiving Primary Care? Substance Abuse 2006, 26: 25-32. PMID: 16687367, DOI: 10.1300/j465v26n02_04.Peer-Reviewed Original ResearchConceptsAST/ALT ratioAlcohol abuse/dependenceMean corpuscular volumeOlder male veteransAbuse/dependenceAlcohol Use Disorders Identification TestCAGE positivityRisk drinkingAlanine aminotransferaseALT ratioAspartate aminotransferaseAlcohol disordersMale veteransPrimary careMedical recordsParticipants' medical recordsAbnormal test resultsTest performance characteristicsDisorders Identification TestPositive likelihood ratioNegative likelihood ratioLikelihood ratioRoutine careVA databasesCAGE questionnaire