Identification of Tumor and Invasion Suppressor Gene Modulators in Bladder Cancer by Different Classes of Histone Deacetylase Inhibitors Using Reverse Phase Protein Arrays
Gould JJ, Kenney PA, Rieger-Christ KM, Neto B, Wszolek MF, LaVoie A, Holway AH, Spurrier B, Austin J, Cammarata BK, Canes D, Libertino JA, Summerhayes IC. Identification of Tumor and Invasion Suppressor Gene Modulators in Bladder Cancer by Different Classes of Histone Deacetylase Inhibitors Using Reverse Phase Protein Arrays. Journal Of Urology 2010, 183: 2395-2402. PMID: 20403623, DOI: 10.1016/j.juro.2010.02.004.Peer-Reviewed Original ResearchMeSH KeywordsGene Expression Regulation, NeoplasticGenes, SuppressorHistone Deacetylase InhibitorsHumansNeoplasm InvasivenessProtein Array AnalysisTumor Cells, CulturedUrinary Bladder NeoplasmsConceptsReverse phase protein arrayPhase protein arrayHistone deacetylase inhibitorsInvasive cell linesDeacetylase inhibitorsProtein arraysExpression profilesCell linesProtein expression profilesMS-275Specific protein groupsSuppressor gene expressionHigh-throughput screeningGene expressionGene modulatorsTrichostatin AInvasive linesSuppressor geneBladder carcinoma cell lineProtein groupsFAK expressionCarcinoma cell linesBladder cancerValproic acidThroughput screening