Novel ZEB1 expression in bladder tumorigenesis
Kenney PA, Wszolek MF, Rieger‐Christ K, Neto BS, Gould JJ, Harty NJ, Mosquera JM, Zeheb R, Loda M, Darling DS, Libertino JA, Summerhayes IC. Novel ZEB1 expression in bladder tumorigenesis. BJU International 2010, 107: 656-663. PMID: 20735391, DOI: 10.1111/j.1464-410x.2010.09489.x.Peer-Reviewed Original ResearchConceptsEpithelial-mesenchymal transitionTransitional cell carcinomaZEB1 expressionNuclear ZEB1 expressionTissue microarrayBladder tumorsTumor progressionGrade I/IIBladder tumorigenesisMuscle-invasive UCBCancer-specific survivalGrade III tumorsNormal bladder mucosaExpression levelsExpression of ZEB1Underlying cellular changesCell linesBladder cell linesUM-UC-3Bladder tumor progressionProtein expression levelsBladder carcinoma cell lineInvasive UCBWestern blot analysisNodal involvement