2021
Cachexia and bladder cancer: clinical impact and management
Lokeshwar SD, Press BH, Nie J, Klaassen Z, Kenney PA, Leapman MS. Cachexia and bladder cancer: clinical impact and management. Current Opinion In Supportive And Palliative Care 2021, 15: 260-265. PMID: 34698663, DOI: 10.1097/spc.0000000000000580.Peer-Reviewed Original ResearchConceptsRadical cystectomyBladder cancerPharmacological agentsManagement of cachexiaNovel pharmaceutical agentsPostoperative complicationsWorse survivalMultidisciplinary managementClinical outcomesHypercatabolic statePalliative carePoor outcomeClinical trialsNutritional supplementationBCa patientsClinical impactPhysical therapyCachexiaRadiation therapyHuman studiesPatientsTherapeutic outcomesNutritional deficienciesNutritional supplementsTumor microenvironmentIncidence, risk factors, and outcome of Clostridioides difficile infection following urological surgeries
Nguyen KA, Le DQ, Bui YT, Advani SD, Renzulli J, Kenney PA, Leapman MS. Incidence, risk factors, and outcome of Clostridioides difficile infection following urological surgeries. World Journal Of Urology 2021, 39: 2995-3003. PMID: 33471163, PMCID: PMC7816064, DOI: 10.1007/s00345-020-03551-y.Peer-Reviewed Original ResearchConceptsNational Surgical Quality Improvement ProgramLength of stayRadical cystectomyUrinary diversionUrological surgeryPostoperative CDIHospital readmissionSurgery typeRisk factorsMultivariable logistic regression analysisSurgical Quality Improvement ProgramPreoperative renal failureRisk of CDISubset of patientsMultivariable logistic regressionIncidence of CDIClostridioides difficile infectionPublic health burdenLogistic regression analysisQuality Improvement ProgramRenal failureSecondary outcomesBlood lossBlood transfusionClinical outcomes
2015
Mucinous tubular and spindle cell carcinoma (MTSCC) of the kidney: a detailed study of radiological, pathological and clinical outcomes
Kenney PA, Vikram R, Prasad SR, Tamboli P, Matin SF, Wood CG, Karam JA. Mucinous tubular and spindle cell carcinoma (MTSCC) of the kidney: a detailed study of radiological, pathological and clinical outcomes. BJU International 2015, 116: 85-92. PMID: 25395040, DOI: 10.1111/bju.12992.Peer-Reviewed Original ResearchConceptsSpindle cell carcinomaCell carcinomaSingle-institution retrospective analysisContrast-enhanced computed tomographyRenal cell carcinoma variantsPT3a diseaseOncological outcomesSalvage surgeryClinical characteristicsMetastatic diseaseFemale predominanceMedian ageClinical outcomesRadical nephrectomyFemale predilectionExcellent outcomesPathological featuresCarcinoma variantsSarcomatoid dedifferentiationActive surveillanceHistological featuresRetrospective analysisEnergy ablationComputed tomographyPapillary RCC