Independent component analysis of resting state activity in pediatric obsessive‐compulsive disorder
Gruner P, Vo A, Argyelan M, Ikuta T, Degnan AJ, John M, Peters BD, Malhotra AK, Uluğ AM, Szeszko PR. Independent component analysis of resting state activity in pediatric obsessive‐compulsive disorder. Human Brain Mapping 2014, 35: 5306-5315. PMID: 24867148, PMCID: PMC4169329, DOI: 10.1002/hbm.22551.Peer-Reviewed Original ResearchConceptsPosterior cingulate networkObsessive-compulsive disorderPediatric obsessive-compulsive disorderHealthy volunteersCingulate networkExpression scoreSpatial group independent component analysisVisual networkState functional magnetic resonanceCourse of illnessHigher expression scoresPediatric OCD patientsAnterior cingulate networkDorsal anterior cingulateFunctional magnetic resonancePatterns of brainGroup independent component analysisPharmacologic interventionsClinical correlatesPatientsAnterior cingulateGreater severityCingulate cortexFMRI abnormalitiesLogistic regression