2000
Identification of a multipotent astrocytic stem cell in the immature and adult mouse brain
Laywell E, Rakic P, Kukekov V, Holland E, Steindler D. Identification of a multipotent astrocytic stem cell in the immature and adult mouse brain. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 13883-13888. PMID: 11095732, PMCID: PMC17670, DOI: 10.1073/pnas.250471697.Peer-Reviewed Original ResearchConceptsCentral nervous systemNeural stem cellsAstrocyte monolayersMultipotent astrocytic stem cellsAstrocytic stem cellsPostnatal central nervous systemAdult mouse brainStem cellsCerebral cortexPostnatal wkSpinal cordAdult brainSubependymal zoneNervous systemEpendymal cellsMouse brainMammalian brainSpherical clonesCNS developmentBrainVivo identificationAstrocytesMature forebrainCritical periodCE cells
1999
Continuation of neurogenesis in the hippocampus of the adult macaque monkey
Kornack D, Rakic P. Continuation of neurogenesis in the hippocampus of the adult macaque monkey. Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 5768-5773. PMID: 10318959, PMCID: PMC21935, DOI: 10.1073/pnas.96.10.5768.Peer-Reviewed Original ResearchConceptsAdult macaque monkeysDentate gyrusMacaque monkeysAdult primate hippocampusAdult rodent dentate gyrusImmunohistochemical double labelingHippocampal dentate gyrusRodent dentate gyrusDiscreet brain regionsMultipotent neural stem cellsNeural stem cellsAdult neurogenesisAdult brainPrimate hippocampusAnimal modelsBrain regionsDouble labelingNeurogenesisSpecific markersHippocampusGyrusStem cellsCell typesMonkeysHumans
1992
Selective Role of N-Type Calcium Channels in Neuronal Migration
Komuro H, Rakic P. Selective Role of N-Type Calcium Channels in Neuronal Migration. Science 1992, 257: 806-809. PMID: 1323145, DOI: 10.1126/science.1323145.Peer-Reviewed Original ResearchConceptsN-type calcium channelsCalcium channelsNeuronal migrationT-type calcium channelsCerebellar slice preparationGranule cell migrationImmature neuronsSelective blockadeSlice preparationPostmitotic granule cellsAdult brainGranule cellsSynaptic circuitsNeurotransmitter releasePotassium channelsPlasmalemmal surfaceIncubation mediumCell migrationSelective roleLaser scanning confocal microscopeScanning confocal microscopeBlockadeSpecific developmental roleNeuronsBrain