m-Chlorophenylpiperazine in patients with obsessive-compulsive disorder: Absence of symptom exacerbation
Goodman W, McDougle C, Price L, Barr L, Hills O, Caplik J, Charney D, Heninger G. m-Chlorophenylpiperazine in patients with obsessive-compulsive disorder: Absence of symptom exacerbation. Biological Psychiatry 1995, 38: 138-149. PMID: 7578657, DOI: 10.1016/0006-3223(94)00235-u.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderDrug-free patientsPlasma prolactin responseSeparate test daysOCD symptomsRatings of anxietySymptom exacerbationIntravenous routeProlactin responseOral administrationSusceptible subgroupsBiochemical measuresObsessive-compulsive symptomsSymptomsRandom orderMCPPTest dayPatientsSignificant increaseDisordersBehavioral findingsFindingsPlaceboExacerbationChlorophenylpiperazine