2023
Comparative Effectiveness of Intracranial Pressure Monitoring on 6-Month Outcomes of Critically Ill Patients With Traumatic Brain Injury
Nattino G, Gamberini L, Brissy O, Carrara G, Chesnut R, Chiarini V, Chieregato A, Csomos A, Fleming J, Gradisek P, Kaps R, Kyprianou T, Lazar I, Lemeshow S, Mikaszewska-Sokolewicz M, Paci G, Rossi C, Temkin N, Xirouchaki N, Giugni A, Bertolini G, Agostini F, Ajmone-Cat C, Bassi G, Bekos V, Bellin M, Bocci M, Bonato V, Bonato A, Bonizzoli M, Bonucci P, Bottazzi A, Calamai I, Calicchio G, Carlin F, Casagli S, Castioni C, Ciceri R, Cocciolo F, Crestan E, Csato G, Cseplo P, Curto F, Dąbrowski W, De Cristofaro A, De Luca A, Duda I, Duek O, Bakó B, Fagoni N, Fassini P, Ferri E, Filekovic S, Fiore G, Gamberini E, Gattari D, Gianni M, Dessena M, Giuntini R, Guido S, Gyulai R, Hadash A, Hribar R, Ilia S, Jankovic V, Jurekovic V, Jereb M, Kapias M, Karadzic D, Kasnik D, Vaggelis V, Szaszi A, Kompan J, Kyriakides E, Lagomarsino S, Lamborghini S, Livigni S, Malacarne P, Martelli M, Martin M, Martino C, Marudi A, Melis M, Mengoli F, Mirkovic T, Mizak W, Munari M, Nardai G, Nascimben E, Natalini G, Negro G, Nemes C, Bernasconi M, Pagani M, Parrini V, Partala P, Pastorelli M, Pellicioli I, Perino Bert P, Petrucci N, Piva S, Poole D, Portolani L, Radrizzani D, Rekas A, Robak P, Rosano A, Ruggeri P, Sacchi M, Sárkány Á, Skoti M, Skrt A, Spagarino E, Sulkowski W, Szedlák B, Terzitta M, Tinturini R, Tofani R, Tselioti P, Vecchiarelli A, Venturini E, Visconti S, Zompanti V, Zoppellari R. Comparative Effectiveness of Intracranial Pressure Monitoring on 6-Month Outcomes of Critically Ill Patients With Traumatic Brain Injury. JAMA Network Open 2023, 6: e2334214. PMID: 37755832, PMCID: PMC10534270, DOI: 10.1001/jamanetworkopen.2023.34214.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryIntensive care unitICP monitoringIntracranial pressureCohort studyBrain injuryGlasgow Outcome Scale Extended scoreBrain Trauma Foundation guidelinesFrequent medical interventionsMid-term outcomesProspective cohort studyDays of injuryRelevant adverse effectsIntracranial pressure monitoringIll patientsMedical therapyCare unitFunctional disabilityPersistent elevationPoor outcomeFoundation guidelinesTreatment choiceMAIN OUTCOMEPressure monitoringPatientsBiological rhythms in COVID-19 vaccine effectiveness in an observational cohort study of 1.5 million patients
Hazan G, Duek O, Alapi H, Mok H, Ganninger A, Ostendorf E, Gierasch C, Chodick G, Greenberg D, Haspel J. Biological rhythms in COVID-19 vaccine effectiveness in an observational cohort study of 1.5 million patients. Journal Of Clinical Investigation 2023, 133: e167339. PMID: 37053011, PMCID: PMC10231992, DOI: 10.1172/jci167339.Peer-Reviewed Original ResearchConceptsCOVID-19 vaccinationBreakthrough infectionsVaccine effectivenessVaccination timingCOVID-19 breakthrough infectionsCOVID-19-related hospitalizationCOVID-19 vaccine effectivenessBasic immune processesSecond booster doseObservational cohort studyEmergency department visitsMass vaccination programBooster doseVaccination timeBooster dosesCohort studyOlder patientsPatient ageDepartment visitsVaccine protectionCox regressionIsraeli cohortClinical endpointsVaccination programImmunization time
2022
Comparative effectiveness of group v. individual trauma-focused treatment for posttraumatic stress disorder in veterans
Spiller TR, Duek O, Buta E, Gross G, Smith NB, Harpaz-Rotem I. Comparative effectiveness of group v. individual trauma-focused treatment for posttraumatic stress disorder in veterans. Psychological Medicine 2022, 53: 4561-4568. PMID: 35959560, PMCID: PMC10388318, DOI: 10.1017/s0033291722001441.Peer-Reviewed Original ResearchConceptsGroup cognitive processing therapyCognitive processing therapyPosttraumatic stress disorderIndividual cognitive processing therapyPTSD symptom severitySymptom severityStress disorderReal-world effectivenessComparative effectiveness studiesResidential treatmentEffective treatmentComparative effectivenessVeterans AffairsEffectiveness studiesPTSD ChecklistPTSD severityGroup therapySeverityVeteransTreatmentDSM-5Group V.TherapyDisordersSmall reduction
2013
Reward sensitivity and anger in euthymic bipolar disorder
Duek O, Osher Y, Belmaker RH, Bersudsky Y, Kofman O. Reward sensitivity and anger in euthymic bipolar disorder. Psychiatry Research 2013, 215: 95-100. PMID: 24230992, DOI: 10.1016/j.psychres.2013.10.028.Peer-Reviewed Original ResearchConceptsSingle Key Impulsivity ParadigmProbabilistic classification taskUltimatum gameReward sensitivityUnfair offersEuthymic stateAdult bipolar disorder patientsBipolar disorderEuthymic bipolar disorderUse of tasksPunishment learningResidual angerApproach systemHC participantsFair offersAngerRewardBipolar disorder patientsHC groupDisorder patientsParticipantsTaskPunishmentClassification taskBAS