1990
Direct carbon versus proton heteronuclear editing of 2‐13C ethanol in rabbit brain in vivo: A sensitivity comparison
Novotny E, Ogino T, Rothman D, Petroff O, Prichard J, Shulman R. Direct carbon versus proton heteronuclear editing of 2‐13C ethanol in rabbit brain in vivo: A sensitivity comparison. Magnetic Resonance In Medicine 1990, 16: 431-443. PMID: 2077334, DOI: 10.1002/mrm.1910160310.Peer-Reviewed Original ResearchProton NMR Observation of Phenylalanine and an Aromatic Metabolite in the Rabbit Brain in Vivo
Avison M, Herschkowitz N, Novotny E, Petroff O, Rothman D, Colombo J, Bachmann C, Shulman R, Prichard J. Proton NMR Observation of Phenylalanine and an Aromatic Metabolite in the Rabbit Brain in Vivo. Pediatric Research 1990, 27: 566-570. PMID: 2162514, DOI: 10.1203/00006450-199006000-00005.Peer-Reviewed Original ResearchNeonatal Excitotoxic Brain Injury
Young R, Petroff O, Novotny E, Wong M. Neonatal Excitotoxic Brain Injury. Developmental Neuroscience 1990, 12: 210-220. PMID: 2142073, DOI: 10.1159/000111850.Peer-Reviewed Original ResearchConceptsQuisqualic acidBrain injuryNeonatal excitotoxic brain injuryExcitotoxic brain injuryHypoxic-ischemic injuryNeonatal rat brainN-acetyl aspartateExcitotoxic damageNeuronal necrosisNeuropathologic examinationParoxysmal dischargesNeonatal ratsElectroencephalographic monitoringHilar areaRat brainMedial CA1Pathologic alterationsMetabolic alterationsParahippocampal regionPathological effectsGlutamate analogueInjuryPhysiologicUnique patternAlterations
1988
Proton magnetic resonance spectroscopic studies of agonal carbohydrate metabolism in rabbit brain.
C. Petroff O, Prichard J, Ogino T, Shulman R. Proton magnetic resonance spectroscopic studies of agonal carbohydrate metabolism in rabbit brain. Neurology 1988, 38: 1569-74. PMID: 3419601, DOI: 10.1212/wnl.38.10.1569.Peer-Reviewed Original ResearchConceptsBlood glucoseCerebral lactate accumulationLactate accumulationProton magnetic resonance spectroscopic studyWet weight/minCerebral metabolismCardiac arrestControl rabbitsRabbit brainGlycolytic rateMagnetic resonance spectroscopic measurementsCarbohydrate metabolismEquivalents/RabbitsMagnetic resonance spectroscopyMetabolismGlucoseCarbohydrate availabilityGlucose equivalent/High‐Resolution Proton Magnetic Resonance Spectroscopy of Rabbit Brain: Regional Metabolite Levels and Postmortem Changes
Petroff O, Ogino T, Alger J. High‐Resolution Proton Magnetic Resonance Spectroscopy of Rabbit Brain: Regional Metabolite Levels and Postmortem Changes. Journal Of Neurochemistry 1988, 51: 163-171. PMID: 3379399, DOI: 10.1111/j.1471-4159.1988.tb04850.x.Peer-Reviewed Original ResearchConceptsN-acetylaspartateWhite matterRabbit cerebral cortexCerebral white matterProton magnetic resonance spectroscopyGamma-aminobutyric acidRegional metabolite levelsTotal creatine poolCardiac arrestCerebral cortexCerebral metabolitesRabbit brainMagnetic resonance spectroscopyCreatine poolMetabolite levelsReference standardPostmortem changesCortexResonance spectroscopy
1987
Cerebral Lactate Elevation by Electroshock: A 1H Magnetic Resonance Studya
PRICHARD J, PETROFF O, OGINO T, SHULMAN R. Cerebral Lactate Elevation by Electroshock: A 1H Magnetic Resonance Studya. Annals Of The New York Academy Of Sciences 1987, 508: 54-63. PMID: 3439712, DOI: 10.1111/j.1749-6632.1987.tb32894.x.Peer-Reviewed Original Research31P magnetization transfer studies of creatine kinase kinetics in living rabbit brain
Degani H, Alger J, Shulman R, Petroff O, Prichard J. 31P magnetization transfer studies of creatine kinase kinetics in living rabbit brain. Magnetic Resonance In Medicine 1987, 5: 1-12. PMID: 3657491, DOI: 10.1002/mrm.1910050102.Peer-Reviewed Original Research
1986
High‐Resolution Proton Magnetic Resonance Analysis of Human Cerebrospinal Fluid
Petroff O, Yu R, Ogino T. High‐Resolution Proton Magnetic Resonance Analysis of Human Cerebrospinal Fluid. Journal Of Neurochemistry 1986, 47: 1270-1276. PMID: 3746301, DOI: 10.1111/j.1471-4159.1986.tb00750.x.Peer-Reviewed Original ResearchCombined 1H and 31P nuclear magnetic resonance spectroscopic studies of bicuculline‐induced seizures in vivo
Petroff O, Prichard J, Ogino T, Avison M, Alger J, Shulman R. Combined 1H and 31P nuclear magnetic resonance spectroscopic studies of bicuculline‐induced seizures in vivo. Annals Of Neurology 1986, 20: 185-193. PMID: 3752964, DOI: 10.1002/ana.410200203.Peer-Reviewed Original ResearchConceptsBicuculline-induced seizuresCerebral intracellular pHArterial blood pressureCerebral lactate levelsIntracellular pHLactate elevationProlonged seizuresBlood pressureParalyzed rabbitsLactate levelsHeart rateSeizuresLactate concentrationComplete recoverySigns of recoveryElectroencephalogramHoursCerebrumMagnetic resonance spectroscopic studiesBrain
1985
Cerebral metabolism in hyper- and hypocarbia: 31P and 1H nuclear magnetic resonance studies.
Petroff O, Prichard J, Behar K, Rothman D, Alger J, Shulman R. Cerebral metabolism in hyper- and hypocarbia: 31P and 1H nuclear magnetic resonance studies. Neurology 1985, 35: 1681-8. PMID: 2933595, DOI: 10.1212/wnl.35.12.1681.Peer-Reviewed Original Research
1984
In vivo phosphorus nuclear magnetic resonance spectroscopy in status epilepticus
Petroff O, Prichard J, Behar K, Alger J, Shulman R. In vivo phosphorus nuclear magnetic resonance spectroscopy in status epilepticus. Annals Of Neurology 1984, 16: 169-177. PMID: 6476792, DOI: 10.1002/ana.410160203.Peer-Reviewed Original ResearchConceptsStatus epilepticusSeizure activityVivo phosphorus nuclear magnetic resonance spectroscopyControl valuesBicuculline-induced status epilepticusAdequate cerebral perfusionAnticonvulsant drug effectsDoses of bicucullineBlood pressureCerebral perfusionSeizure dischargesPhosphorus nuclear magnetic resonance spectroscopyPhosphocreatine levelsParalyzed rabbitsBrain phosphocreatineDrug effectsNitrous oxide mixtureEpilepticusTriphosphate levelsVivo brainTwo-thirdsPhysiological variablesMagnetic resonance spectroscopyGradual declineIntracellularDetection of cerebral lactate in vivo during hypoxemia by 1H NMR at relatively low field strengths (1.9 T).
Behar K, Rothman D, Shulman R, Petroff O, Prichard J. Detection of cerebral lactate in vivo during hypoxemia by 1H NMR at relatively low field strengths (1.9 T). Proceedings Of The National Academy Of Sciences Of The United States Of America 1984, 81: 2517-2519. PMID: 6585812, PMCID: PMC345093, DOI: 10.1073/pnas.81.8.2517.Peer-Reviewed Original Research