1988
High‐Resolution Proton Magnetic Resonance Spectroscopy of Rabbit Brain: Regional Metabolite Levels and Postmortem Changes
Petroff O, Ogino T, Alger J. High‐Resolution Proton Magnetic Resonance Spectroscopy of Rabbit Brain: Regional Metabolite Levels and Postmortem Changes. Journal Of Neurochemistry 1988, 51: 163-171. PMID: 3379399, DOI: 10.1111/j.1471-4159.1988.tb04850.x.Peer-Reviewed Original ResearchConceptsN-acetylaspartateWhite matterRabbit cerebral cortexCerebral white matterProton magnetic resonance spectroscopyGamma-aminobutyric acidRegional metabolite levelsTotal creatine poolCardiac arrestCerebral cortexCerebral metabolitesRabbit brainMagnetic resonance spectroscopyCreatine poolMetabolite levelsReference standardPostmortem changesCortexResonance spectroscopy
1987
In vivo 31P and in vitro 1H nuclear magnetic resonance study of hypoglycemia during neonatal seizure
Young R, Cowan B, Petroff O, Novotny E, Dunham S, Briggs R. In vivo 31P and in vitro 1H nuclear magnetic resonance study of hypoglycemia during neonatal seizure. Annals Of Neurology 1987, 22: 622-628. PMID: 3426168, DOI: 10.1002/ana.410220511.Peer-Reviewed Original ResearchConceptsNeonatal seizuresBrain energy stateBicuculline-induced seizuresBrain glucose concentrationsCerebral blood flowBeta-hydroxybutyrate levelsBrain metabolic stateVivo 31P nuclear magnetic resonance spectroscopyBrain alanineAdenosine triphosphate levelsNeonatal dogsPhosphocreatine levelsSignificant elevationBlood flowSeizuresMagnetic resonance spectroscopyBrain extractsVivo 31PHypoglycemiaAdverse effectsTriphosphate levelsGlucose concentrationGreater declineFurther deteriorationMetabolic state
1986
Combined 1H and 31P nuclear magnetic resonance spectroscopic studies of bicuculline‐induced seizures in vivo
Petroff O, Prichard J, Ogino T, Avison M, Alger J, Shulman R. Combined 1H and 31P nuclear magnetic resonance spectroscopic studies of bicuculline‐induced seizures in vivo. Annals Of Neurology 1986, 20: 185-193. PMID: 3752964, DOI: 10.1002/ana.410200203.Peer-Reviewed Original ResearchConceptsBicuculline-induced seizuresCerebral intracellular pHArterial blood pressureCerebral lactate levelsIntracellular pHLactate elevationProlonged seizuresBlood pressureParalyzed rabbitsLactate levelsHeart rateSeizuresLactate concentrationComplete recoverySigns of recoveryElectroencephalogramHoursCerebrumMagnetic resonance spectroscopic studiesBrain
1985
Effect of Hypoglycemic Encephalopathy upon Amino Acids, High‐Energy Phosphates, and pHi in the Rat Brain In Vivo: Detection by Sequential 1H and 31P NMR Spectroscopy
Behar K, Hollander J, Petroff O, Hetherington H, Prichard J, Shulman R. Effect of Hypoglycemic Encephalopathy upon Amino Acids, High‐Energy Phosphates, and pHi in the Rat Brain In Vivo: Detection by Sequential 1H and 31P NMR Spectroscopy. Journal Of Neurochemistry 1985, 44: 1045-1055. PMID: 2857770, DOI: 10.1111/j.1471-4159.1985.tb08723.x.Peer-Reviewed Original Research1H-Observe/13C-decouple spectroscopic measurements of lactate and glutamate in the rat brain in vivo.
Rothman D, Behar K, Hetherington H, Hollander J, Bendall M, Petroff O, Shulman R. 1H-Observe/13C-decouple spectroscopic measurements of lactate and glutamate in the rat brain in vivo. Proceedings Of The National Academy Of Sciences Of The United States Of America 1985, 82: 1633-1637. PMID: 2858850, PMCID: PMC397326, DOI: 10.1073/pnas.82.6.1633.Peer-Reviewed Original Research
1984
Detection of cerebral lactate in vivo during hypoxemia by 1H NMR at relatively low field strengths (1.9 T).
Behar K, Rothman D, Shulman R, Petroff O, Prichard J. Detection of cerebral lactate in vivo during hypoxemia by 1H NMR at relatively low field strengths (1.9 T). Proceedings Of The National Academy Of Sciences Of The United States Of America 1984, 81: 2517-2519. PMID: 6585812, PMCID: PMC345093, DOI: 10.1073/pnas.81.8.2517.Peer-Reviewed Original Research
1983
High-resolution 1H nuclear magnetic resonance study of cerebral hypoxia in vivo.
Behar K, Hollander J, Stromski M, Ogino T, Shulman R, Petroff O, Prichard J. High-resolution 1H nuclear magnetic resonance study of cerebral hypoxia in vivo. Proceedings Of The National Academy Of Sciences Of The United States Of America 1983, 80: 4945-4948. PMID: 6576367, PMCID: PMC384164, DOI: 10.1073/pnas.80.16.4945.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCerebral CortexHeart RateHypoxiaKineticsLactatesLactic AcidMagnetic Resonance SpectroscopyRats