1990
Direct carbon versus proton heteronuclear editing of 2‐13C ethanol in rabbit brain in vivo: A sensitivity comparison
Novotny E, Ogino T, Rothman D, Petroff O, Prichard J, Shulman R. Direct carbon versus proton heteronuclear editing of 2‐13C ethanol in rabbit brain in vivo: A sensitivity comparison. Magnetic Resonance In Medicine 1990, 16: 431-443. PMID: 2077334, DOI: 10.1002/mrm.1910160310.Peer-Reviewed Original ResearchProton NMR Observation of Phenylalanine and an Aromatic Metabolite in the Rabbit Brain in Vivo
Avison M, Herschkowitz N, Novotny E, Petroff O, Rothman D, Colombo J, Bachmann C, Shulman R, Prichard J. Proton NMR Observation of Phenylalanine and an Aromatic Metabolite in the Rabbit Brain in Vivo. Pediatric Research 1990, 27: 566-570. PMID: 2162514, DOI: 10.1203/00006450-199006000-00005.Peer-Reviewed Original ResearchIn Vivo Measurements of Ethanol Concentration in Rabbit Brain by 1H Magnetic Resonance Spectroscopy
Petroff O, Novotny E, Ogino T, Avison M, Prichard J. In Vivo Measurements of Ethanol Concentration in Rabbit Brain by 1H Magnetic Resonance Spectroscopy. Journal Of Neurochemistry 1990, 54: 1188-1195. PMID: 2313285, DOI: 10.1111/j.1471-4159.1990.tb01947.x.Peer-Reviewed Original ResearchConceptsMagnetic resonance spectroscopyResonance spectroscopyChemical Shift Selective Magnetic Resonance ImagingVivo 1H magnetic resonance spectroscopyCerebral blood flowBlood ethanol concentrationVivo 1H spectroscopyMagnetic resonance imagingIntragastric administrationBlood flowGas chromatographyRabbit brainResonance imagingSpectroscopyPerchloric acid extractsEthanol levelsAdministrationBrainAcid extractsVivo measurementsCerebralEthanol concentration
1988
Proton magnetic resonance spectroscopic studies of agonal carbohydrate metabolism in rabbit brain.
C. Petroff O, Prichard J, Ogino T, Shulman R. Proton magnetic resonance spectroscopic studies of agonal carbohydrate metabolism in rabbit brain. Neurology 1988, 38: 1569-74. PMID: 3419601, DOI: 10.1212/wnl.38.10.1569.Peer-Reviewed Original ResearchConceptsBlood glucoseCerebral lactate accumulationLactate accumulationProton magnetic resonance spectroscopic studyWet weight/minCerebral metabolismCardiac arrestControl rabbitsRabbit brainGlycolytic rateMagnetic resonance spectroscopic measurementsCarbohydrate metabolismEquivalents/RabbitsMagnetic resonance spectroscopyMetabolismGlucoseCarbohydrate availabilityGlucose equivalent/High‐Resolution Proton Magnetic Resonance Spectroscopy of Rabbit Brain: Regional Metabolite Levels and Postmortem Changes
Petroff O, Ogino T, Alger J. High‐Resolution Proton Magnetic Resonance Spectroscopy of Rabbit Brain: Regional Metabolite Levels and Postmortem Changes. Journal Of Neurochemistry 1988, 51: 163-171. PMID: 3379399, DOI: 10.1111/j.1471-4159.1988.tb04850.x.Peer-Reviewed Original ResearchConceptsN-acetylaspartateWhite matterRabbit cerebral cortexCerebral white matterProton magnetic resonance spectroscopyGamma-aminobutyric acidRegional metabolite levelsTotal creatine poolCardiac arrestCerebral cortexCerebral metabolitesRabbit brainMagnetic resonance spectroscopyCreatine poolMetabolite levelsReference standardPostmortem changesCortexResonance spectroscopy
1987
Cerebral Lactate Elevation by Electroshock: A 1H Magnetic Resonance Studya
PRICHARD J, PETROFF O, OGINO T, SHULMAN R. Cerebral Lactate Elevation by Electroshock: A 1H Magnetic Resonance Studya. Annals Of The New York Academy Of Sciences 1987, 508: 54-63. PMID: 3439712, DOI: 10.1111/j.1749-6632.1987.tb32894.x.Peer-Reviewed Original Research31P magnetization transfer studies of creatine kinase kinetics in living rabbit brain
Degani H, Alger J, Shulman R, Petroff O, Prichard J. 31P magnetization transfer studies of creatine kinase kinetics in living rabbit brain. Magnetic Resonance In Medicine 1987, 5: 1-12. PMID: 3657491, DOI: 10.1002/mrm.1910050102.Peer-Reviewed Original Research
1986
Detection of metabolites in rabbit brain by 13C NMR spectroscopy following administration of [1‐13C]glucose
Behar K, Petroff O, Prichard J, Alger J, Shulman R. Detection of metabolites in rabbit brain by 13C NMR spectroscopy following administration of [1‐13C]glucose. Magnetic Resonance In Medicine 1986, 3: 911-920. PMID: 2881185, DOI: 10.1002/mrm.1910030611.Peer-Reviewed Original ResearchCombined 1H and 31P nuclear magnetic resonance spectroscopic studies of bicuculline‐induced seizures in vivo
Petroff O, Prichard J, Ogino T, Avison M, Alger J, Shulman R. Combined 1H and 31P nuclear magnetic resonance spectroscopic studies of bicuculline‐induced seizures in vivo. Annals Of Neurology 1986, 20: 185-193. PMID: 3752964, DOI: 10.1002/ana.410200203.Peer-Reviewed Original ResearchConceptsBicuculline-induced seizuresCerebral intracellular pHArterial blood pressureCerebral lactate levelsIntracellular pHLactate elevationProlonged seizuresBlood pressureParalyzed rabbitsLactate levelsHeart rateSeizuresLactate concentrationComplete recoverySigns of recoveryElectroencephalogramHoursCerebrumMagnetic resonance spectroscopic studiesBrain
1985
Cerebral metabolism in hyper- and hypocarbia: 31P and 1H nuclear magnetic resonance studies.
Petroff O, Prichard J, Behar K, Rothman D, Alger J, Shulman R. Cerebral metabolism in hyper- and hypocarbia: 31P and 1H nuclear magnetic resonance studies. Neurology 1985, 35: 1681-8. PMID: 2933595, DOI: 10.1212/wnl.35.12.1681.Peer-Reviewed Original ResearchCerebral intracellular pH by 31P nuclear magnetic resonance spectroscopy.
Petroff O, Prichard J, Behar K, Alger J, den Hollander J, Shulman R. Cerebral intracellular pH by 31P nuclear magnetic resonance spectroscopy. Neurology 1985, 35: 781-8. PMID: 4000479, DOI: 10.1212/wnl.35.6.781.Peer-Reviewed Original Research
1984
In vivo phosphorus nuclear magnetic resonance spectroscopy in status epilepticus
Petroff O, Prichard J, Behar K, Alger J, Shulman R. In vivo phosphorus nuclear magnetic resonance spectroscopy in status epilepticus. Annals Of Neurology 1984, 16: 169-177. PMID: 6476792, DOI: 10.1002/ana.410160203.Peer-Reviewed Original ResearchConceptsStatus epilepticusSeizure activityVivo phosphorus nuclear magnetic resonance spectroscopyControl valuesBicuculline-induced status epilepticusAdequate cerebral perfusionAnticonvulsant drug effectsDoses of bicucullineBlood pressureCerebral perfusionSeizure dischargesPhosphorus nuclear magnetic resonance spectroscopyPhosphocreatine levelsParalyzed rabbitsBrain phosphocreatineDrug effectsNitrous oxide mixtureEpilepticusTriphosphate levelsVivo brainTwo-thirdsPhysiological variablesMagnetic resonance spectroscopyGradual declineIntracellularDetection of cerebral lactate in vivo during hypoxemia by 1H NMR at relatively low field strengths (1.9 T).
Behar K, Rothman D, Shulman R, Petroff O, Prichard J. Detection of cerebral lactate in vivo during hypoxemia by 1H NMR at relatively low field strengths (1.9 T). Proceedings Of The National Academy Of Sciences Of The United States Of America 1984, 81: 2517-2519. PMID: 6585812, PMCID: PMC345093, DOI: 10.1073/pnas.81.8.2517.Peer-Reviewed Original Research
1983
Cerebral metabolic studies in vivo by 31P NMR.
Prichard J, Alger J, Behar K, Petroff O, Shulman R. Cerebral metabolic studies in vivo by 31P NMR. Proceedings Of The National Academy Of Sciences Of The United States Of America 1983, 80: 2748-2751. PMID: 6573678, PMCID: PMC393905, DOI: 10.1073/pnas.80.9.2748.Peer-Reviewed Original ResearchConceptsStatus epilepticusCerebral metabolic studiesNitrous oxide analgesiaHypoxic hypoxiaMetabolic disturbancesCardiovascular functionInsulin shockEpilepticusHypoglycemiaLiving rabbitsCreatine kinaseMetabolic stressPhosphocreatine storesHypoxiaMetabolic studiesADP levelsATP levelsReversible decreaseSimilar changesPhosphocreatine poolBrainPhysiological variablesSurface coilAnalgesia