2019
Estrogen signaling and estrogen receptors as prognostic indicators in laryngeal cancer
Verma A, Schwartz N, Cohen DJ, Boyan BD, Schwartz Z. Estrogen signaling and estrogen receptors as prognostic indicators in laryngeal cancer. Steroids 2019, 152: 108498. PMID: 31539535, DOI: 10.1016/j.steroids.2019.108498.Peer-Reviewed Original ResearchConceptsSex hormone receptorsEstrogen receptorBreast cancerHormone receptorsCanonical estrogen receptorsAnti-estrogen therapyLoss of ERαSquamous cell carcinomaEstrogen receptor αHormone therapyPrognostic valueCell carcinomaPrognostic indicatorLaryngeal cancerPrognostic markerSex hormonesLSCC tumorsEstrogen signalingReceptor αTumor growthPathogenic markersEnhanced aggressionImportant modulatorERαCancer
2013
Role of ERα36 in membrane-associated signaling by estrogen
Chaudhri RA, Schwartz N, Elbaradie K, Schwartz Z, Boyan BD. Role of ERα36 in membrane-associated signaling by estrogen. Steroids 2013, 81: 74-80. PMID: 24252378, DOI: 10.1016/j.steroids.2013.10.020.Peer-Reviewed Original ResearchConceptsCell typesPlasma membraneAlternative splicing variantsRole of ERα36Non-genomic responsesDifferent cell typesMembrane-associated receptorsCancer cell typesPhosphorylation cascadeTranscription factorsProtein kinaseCellular developmentGene transcriptionApoptotic signalingSplicing variantsCellular responsesNon-classical receptorsNon-classical mechanismNuclear receptorsSimilar pathwaysCell proliferationSteroid hormonesNormal cellsEstrogen receptor αTraditional receptors