2011
Testosterone lowers microvascular ET‐B receptor responsiveness in women with PCOS
Wenner M, Taylor H, Stachenfeld N. Testosterone lowers microvascular ET‐B receptor responsiveness in women with PCOS. The FASEB Journal 2011, 25: lb559-lb559. DOI: 10.1096/fasebj.25.1_supplement.lb559.Peer-Reviewed Original ResearchPolycystic ovary syndromeHeat-induced vasodilationT administrationCutaneous vascular conductance responsesET-1 plasma concentrationsET-B receptor antagonistImpaired microvascular functionET-B receptorsVascular conductance responsesEndogenous sex hormonesLaser Doppler flowmetryPCOS showOvary syndromeGnRH antagonistMicrovascular functionVascular dysfunctionReceptor antagonistReceptor responsivenessMicrodialysis infusionSex hormonesPlasma concentrationsDoppler flowmetryReceptor sensitivityT exposureTestosterone exposure
2010
Greater Orthostatic Tolerance in Young Black Compared With White Women
Hinds K, Stachenfeld NS. Greater Orthostatic Tolerance in Young Black Compared With White Women. Hypertension 2010, 56: 75-81. PMID: 20458005, PMCID: PMC2909588, DOI: 10.1161/hypertensionaha.110.150011.Peer-Reviewed Original ResearchConceptsLower body negative pressureBody negative pressureOrthostatic toleranceWhite womenHeart rateGreater sympathetic nervous system responseR intervalSympathetic nervous system responsesPlasma renin activityPlasma catecholamine concentrationsSerum aldosterone concentrationNervous system responsesNegative pressureBlack womenCumulative stress indexWoman underwentRenin activityAldosterone concentrationBaroreflex functionBlood pressureCatecholamine concentrationsOrthostatic challengePlasma concentrationsHealthy blacksBlood samples
2005
Progesterone increases plasma volume independent of estradiol
Stachenfeld NS, Taylor HS. Progesterone increases plasma volume independent of estradiol. Journal Of Applied Physiology 2005, 98: 1991-1997. PMID: 15718411, DOI: 10.1152/japplphysiol.00031.2005.Peer-Reviewed Original ResearchConceptsTranscapillary escape ratePlasma concentrationsPlasma volumeGnRH antagonistECF volumeAdequate plasma volumeAldosterone system stimulationPlasma renin activityGonadotropin-releasing hormoneExtracellular fluid volumeRenin activitySerum aldosteroneAng IIBlood pressureEstrogen administrationSystem stimulationDay 2Day 5Pg/Day 13Fluid regulationPV expansionFluid volumeIndependent effectsProgesterone
1999
Physiological variability of fluid-regulation hormones in young women
Stachenfeld N, DiPietro L, Kokoszka C, Silva C, Keefe D, Nadel E. Physiological variability of fluid-regulation hormones in young women. Journal Of Applied Physiology 1999, 86: 1092-1096. PMID: 10066728, DOI: 10.1152/jappl.1999.86.3.1092.Peer-Reviewed Original ResearchConceptsPlasma renin activityEarly follicular phaseFollicular phaseMenstrual phaseMenstrual phase-related differencesAtrial natriuretic peptideDifferent menstrual phasesMean hormone concentrationsRenin activityNatriuretic peptideMidluteal phaseMenstrual cycleHormonal variablesPlasma concentrationsLuteal phaseHormone concentrationsPhase-related differencesYoung womenHormoneCronbach's alphaRehydration periodRestingAlphaMean concentrationPhysiological variability