Dihydropyrimidine dehydrogenase gene (DPYD) polymorphism among Caucasian patients (pts) with 5-FU and capecitabine (CAP)-related toxicity
Podoltsev N, Saif M. Dihydropyrimidine dehydrogenase gene (DPYD) polymorphism among Caucasian patients (pts) with 5-FU and capecitabine (CAP)-related toxicity. Journal Of Clinical Oncology 2009, 27: e14588-e14588. DOI: 10.1200/jco.2009.27.15_suppl.e14588.Peer-Reviewed Original ResearchDeleterious mutationsCommon deleterious mutationSequence variationSequence analysisFull sequence analysisGenetic variantsMutationsFull sequencingDihydropyrimidine dehydrogenase gene polymorphismsDPYD mutationsGenetics laboratoriesSimple identificationDPYDDPYD geneGenesD949VSequencingDNAEnzymeToxicityIVS14CatabolismSequencePolymorphismBlood cells