2020
Propranolol Relieves L-Dopa-Induced Dyskinesia in Parkinsonian Mice
Shi Z, Bamford IJ, McKinley JW, Devi SPS, Vahedipour A, Bamford NS. Propranolol Relieves L-Dopa-Induced Dyskinesia in Parkinsonian Mice. Brain Sciences 2020, 10: 903. PMID: 33255421, PMCID: PMC7760026, DOI: 10.3390/brainsci10120903.Peer-Reviewed Original ResearchL-DOPA-induced dyskinesiaL-DOPAStriatal acetylcholineDA deficiencyMovement disordersDA availabilityHypokinetic movement disordersStriatal cholinergic interneuronsHyperkinetic movement disordersDopa decarboxylase inhibitorElectrophysiological experimentsOpen field testingStriatal ChIsParkinsonian miceCholinergic interneuronsMotor dysfunctionTherapeutic optionsMotor hyperactivityParadoxical riseDA ratioMotor functionDecarboxylase inhibitorDopamine insufficiencyΒ-ARsΒ-AR
2018
Treatment of Neurological Symptoms in Wilson Disease
Vives-Rodriguez A, Robakis D, Bamford N. Treatment of Neurological Symptoms in Wilson Disease. Clinical Gastroenterology 2018, 107-120. DOI: 10.1007/978-3-319-91527-2_6.Peer-Reviewed Original ResearchNeurological symptomsWilson's diseaseNeurological manifestationsTherapeutic optionsMovement disordersCommon neurological manifestationsDifferent therapeutic optionsResidual neurological symptomsUse of medicationsBrain copper accumulationQuality of lifeGait impairmentPartial improvementNeurological aspectsSymptomsDiseaseDisordersManifestationsCopper accumulationMost casesMedicationsDystoniaParkinsonismPatientsOptions