2021
A murine model of the human CREBRFR457Q obesity-risk variant does not influence energy or glucose homeostasis in response to nutritional stress
Kanshana JS, Mattila PE, Ewing MC, Wood AN, Schoiswohl G, Meyer AC, Kowalski A, Rosenthal SL, Gingras S, Kaufman BA, Lu R, Weeks DE, McGarvey ST, Minster RL, Hawley NL, Kershaw EE. A murine model of the human CREBRFR457Q obesity-risk variant does not influence energy or glucose homeostasis in response to nutritional stress. PLOS ONE 2021, 16: e0251895. PMID: 34520472, PMCID: PMC8439463, DOI: 10.1371/journal.pone.0251895.Peer-Reviewed Original ResearchConceptsMurine modelGlucose homeostasisEnergy/glucose homeostasisOdds of diabetesOdds of obesityObesity risk variantsAlternative preclinical modelsPromotes obesityPreclinical modelsKnockin miceObesityDiabetesStrong heritable componentExtensive phenotypic analysisMissense variantsOrthologous variantDiseaseMiceOddsAdaptive transcriptional responseExtreme nutritional stressNutritional stressHomeostasisGenetic contributionRegulatory factors
2016
The growing threat of non-communicable disease to pregnancy health
Hawley N. The growing threat of non-communicable disease to pregnancy health. Pacific Journal Of Reproductive Health 2016, 1 DOI: 10.18313/pjrh.2016.909.Peer-Reviewed Original ResearchNon-communicable diseasesChild health effortsPrevalence of obesityRelated non-communicable diseasesSkilled health providersChronic hypertensionObstetric populationMaternal deathsNewborn deathsPregnancy healthPregnant womenGlobal maternalHealth effortsHealth providersAdequate nutritionEssential medicinesDiseaseDeathHypertensionPrematurityObesityDiabetesMaternalMortalityPrevalence
2015
Obesity and Diabetes in Pacific Islanders: the Current Burden and the Need for Urgent Action
Hawley NL, McGarvey ST. Obesity and Diabetes in Pacific Islanders: the Current Burden and the Need for Urgent Action. Current Diabetes Reports 2015, 15: 29. PMID: 25809458, DOI: 10.1007/s11892-015-0594-5.Peer-Reviewed Original Research