2024
Environmental, socioeconomic, and health factors associated with gut microbiome species and strains in isolated Honduras villages
Shridhar S, Beghini F, Alexander M, Singh A, Juárez R, Brito I, Christakis N. Environmental, socioeconomic, and health factors associated with gut microbiome species and strains in isolated Honduras villages. Cell Reports 2024, 43: 114442. PMID: 38968070, PMCID: PMC11290354, DOI: 10.1016/j.celrep.2024.114442.Peer-Reviewed Original ResearchGut microbiomeGut microbiome speciesSpecies-level profilingSequenced microbiomesMetagenomic dataMicrobiome speciesHost phenotypeBacterial speciesHuman phenotypesMesoamerican highlandsSeveral speciesGutSpeciesMicrobiomePhenotypeAssociated with body mass indexCommunity-based cohortBody mass indexConsistent with previous findingsSocioeconomic factorsIsolated villagesHousehold wealthMass indexHostStrainSimple autonomous agents can enhance creative semantic discovery by human groups
Ueshima A, Jones M, Christakis N. Simple autonomous agents can enhance creative semantic discovery by human groups. Nature Communications 2024, 15: 5212. PMID: 38890368, PMCID: PMC11189566, DOI: 10.1038/s41467-024-49528-y.Peer-Reviewed Original ResearchThe structure and function of antagonistic ties in village social networks
Ghasemian A, Christakis N. The structure and function of antagonistic ties in village social networks. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2401257121. PMID: 38889155, PMCID: PMC11214085, DOI: 10.1073/pnas.2401257121.Peer-Reviewed Original ResearchConceptsNegative tiesVillage social networksSocial networksFunction of social networksVillage networkAntagonistic tiesSmall-world effectSurvey wavesRural villagesTiesAntagonistic relationshipHuman social networksHuman groupsVillagePositive worldPositive connectionEmpirical dataHighest betweenness centralityNetwork bridgeDissemination of informationNetworkBetweenness centralityShorter average distanceNodesWorldMaternal and child health intervention to promote behaviour change: a population-level cluster-randomised controlled trial in Honduras
Oles W, Alexander M, Negron R, Nelson J, Iriarte E, Airoldi E, Christakis N, Forastiere L. Maternal and child health intervention to promote behaviour change: a population-level cluster-randomised controlled trial in Honduras. BMJ Open 2024, 14: e060784. PMID: 38858139, PMCID: PMC11168147, DOI: 10.1136/bmjopen-2022-060784.Peer-Reviewed Original ResearchConceptsCluster randomised controlled trialPrimary outcomeCounseling interventionChild health interventionsCommunity health workersProfessional care seekingBreast-feedingPromote behavior changeSecondary outcome measuresFacility birthsUmbilical cord careCare-seekingNewborn healthNewborn careHealth workersHealth facilitiesEndline surveyHealth interventionsEducational interventionChild healthCord careHome settingCaring behaviorsSecondary outcomesSustained educational interventionsInduction of social contagion for diverse outcomes in structured experiments in isolated villages
Airoldi E, Christakis N. Induction of social contagion for diverse outcomes in structured experiments in isolated villages. Science 2024, 384: eadi5147. PMID: 38696582, DOI: 10.1126/science.adi5147.Peer-Reviewed Original ResearchSystematic review of methods to discern antagonistic ties in social networks in community settings
de la Rosa A, Cortez K, Lu A, Valentin B, Ghasemian A, Christakis N. Systematic review of methods to discern antagonistic ties in social networks in community settings. Social Sciences & Humanities Open 2024, 10: 101039. DOI: 10.1016/j.ssaho.2024.101039.Peer-Reviewed Original ResearchCommunity settingsSystematic reviewMethodological systematic reviewSystematic review of methodsNewcastle-Ottawa ScaleWell-being outcomesPhysical/mental healthValidity of measuresStudy characteristicsNewcastle-OttawaPRISMA guidelinesImprove consensusHealthBlinded reviewersQuality assessmentMapping social networksFace-to-face relationshipsSocial networksGood qualityNegative tiesCommunityPhysical/mentalSetsAscertainmentPRISMA
2023
Emergence and collapse of reciprocity in semiautomatic driving coordination experiments with humans
Shirado H, Kasahara S, Christakis N. Emergence and collapse of reciprocity in semiautomatic driving coordination experiments with humans. Proceedings Of The National Academy Of Sciences Of The United States Of America 2023, 120: e2307804120. PMID: 38079552, PMCID: PMC10743379, DOI: 10.1073/pnas.2307804120.Peer-Reviewed Original ResearchConceptsMachine intelligenceNorm of reciprocitySocial reciprocityNormative commitmentSocial coordinationHuman altruismNegative social repercussionsOnline participantsSocial normsCollective outcomesIndividual safetyCoordination experimentsCoordination gameSocial repercussionsIntelligenceHuman agencyAssistance systemsReciprocityHuman groupsTacit understandingPeopleAssistive technologyCollective challengesCollective action problemsLab experimentsStatus invisibility alleviates the economic gradient in happiness in social network experiments
Nishi A, German C, Iwamoto S, Christakis N. Status invisibility alleviates the economic gradient in happiness in social network experiments. Nature Mental Health 2023, 1: 990-1000. DOI: 10.1038/s44220-023-00159-0.Peer-Reviewed Original ResearchThe enmity paradox
Ghasemian A, Christakis N. The enmity paradox. Scientific Reports 2023, 13: 20040. PMID: 37973933, PMCID: PMC10654772, DOI: 10.1038/s41598-023-47167-9.Peer-Reviewed Original ResearchApproaching disease transmission with network science
Vishnempet Shridhar S, Christakis N. Approaching disease transmission with network science. Nature Reviews Bioengineering 2023, 2: 6-7. DOI: 10.1038/s44222-023-00139-0.Peer-Reviewed Original ResearchClinically relevant antibiotic resistance genes are linked to a limited set of taxa within gut microbiome worldwide
Diebold P, Rhee M, Shi Q, Trung N, Umrani F, Ahmed S, Kulkarni V, Deshpande P, Alexander M, Thi Hoa N, Christakis N, Iqbal N, Ali S, Mathad J, Brito I. Clinically relevant antibiotic resistance genes are linked to a limited set of taxa within gut microbiome worldwide. Nature Communications 2023, 14: 7366. PMID: 37963868, PMCID: PMC10645880, DOI: 10.1038/s41467-023-42998-6.Peer-Reviewed Original ResearchConceptsResistance genesSet of genesGut microbiome samplesHuman gut microbiomeGut microbiotaTaxonomic rangeEnvironmental metagenomesDifferent phylaGut microbiomeTaxonomic associationsIsolate genomesAntibiotic resistance genesAR geneRelevant antibiotic resistance genesGenesDiverse membersHuman metagenomesMicrobiome samplesPCR approachGene profilesAntimicrobial resistance genesCommensal gut microbiotaMobilizable plasmidsMetagenomesImportant pathogenEmergency communications after earthquake reveal social network backbone of important ties
Jia J, Li Y, Liu S, Christakis N, Jia J. Emergency communications after earthquake reveal social network backbone of important ties. PNAS Nexus 2023, 2: pgad358. PMID: 38024411, PMCID: PMC10658761, DOI: 10.1093/pnasnexus/pgad358.Peer-Reviewed Original Research