Application of glutamate weighted CEST in brain imaging of nicotine dependent participants in vivo at 7T
Jacobs P, Jee J, Fang L, Devlin E, Iannelli C, Thakuri D, Loughead J, Epperson C, Wilson N, Roalf D, Reddy R, Nanga R. Application of glutamate weighted CEST in brain imaging of nicotine dependent participants in vivo at 7T. PLOS ONE 2024, 19: e0297310. PMID: 38363747, PMCID: PMC10871471, DOI: 10.1371/journal.pone.0297310.Peer-Reviewed Original ResearchConceptsDorsal anterior cingulate cortexNon-smokersCingulate gyrusAnterior cingulate cortexContext of addictionTreating nicotine addictionApplication of glutamatePopulation of smokersWilcoxon rank sum testGluCEST imagingTraumatic brain injuryT1-weighted imagesInvestigated glutamateSignificant healthcare issueCingulate cortexGray matter regionsRank sum testNicotine useNicotine addictionNicotine dependenceBrain regionsChemical exchange saturation transferNegative age dependenceHealthy participantsUltra-high field MRI