Maternal adverse childhood experiences and infant visual-limbic white matter development
Demers C, Hankin B, Haase M, Todd E, Hoffman M, Epperson C, Styner M, Davis E. Maternal adverse childhood experiences and infant visual-limbic white matter development. Journal Of Affective Disorders 2024, 367: 49-57. PMID: 39191307, DOI: 10.1016/j.jad.2024.08.146.Peer-Reviewed Original ResearchMaternal adverse childhood experiencesAdverse childhood experiencesInferior longitudinal fasciculusFractional anisotropyLongitudinal fasciculusChildhood experiencesLeft inferior longitudinal fasciculusStructural magnetic resonance imagingPredictors of mental healthVisual processing networksNo group differencesExploratory analysisChildhood questionnaireEarly life adversity exposuresWhite matter microstructureMother-infant dyadsFollow-up analysisCognitive circuitsPreliminary supportNeural circuit developmentInfant brain developmentMagnetic resonance imagingGroup differencesSensory processingIntergenerational riskSex differences in stress-induced cortisol response among infants of mothers exposed to childhood adversity
Duffy K, Sammel M, Johnson R, Morrison K, Bale T, Epperson C. Sex differences in stress-induced cortisol response among infants of mothers exposed to childhood adversity. Biological Psychiatry 2024, 96: 876-885. PMID: 38821195, DOI: 10.1016/j.biopsych.2024.05.015.Peer-Reviewed Original ResearchAdverse childhood experiencesMother-infant dyadsCortisol responseSex differencesAssociated with lower cortisol responsesHypothalamic-pituitary-adrenal (HPA) axisStress-induced cortisol responseExposure to childhood abuseSix-month-old infantsAdverse Childhood Experiences QuestionnaireInfants of mothersLow cortisol responseMeasured salivary cortisolSignificant sex differencesImpact of adverse childhood experiencesInfant cortisolChildhood abuseLaboratory stressorHPA axisChildhood adversityMental illnessChildhood experiencesSalivary cortisolAbuseStressors