2023
The Clinical Utility of Genetic Testing in the Diagnosis and Management of Adults with Chronic Kidney Disease
Dahl N, Bloom M, Chebib F, Clark D, Westemeyer M, Jandeska S, Zhang Z, Milo-Rasouly H, Kolupaeva V, Marasa M, Broumand V, Fatica R, Raj D, Demko Z, Marshall K, Punj S, Tabriziani H, Bhorade S, Gharavi A. The Clinical Utility of Genetic Testing in the Diagnosis and Management of Adults with Chronic Kidney Disease. Journal Of The American Society Of Nephrology 2023, 34: 2039-2050. PMID: 37794564, PMCID: PMC10703084, DOI: 10.1681/asn.0000000000000249.Peer-Reviewed Original ResearchConceptsPositive genetic findingsCKD diagnosisGenetic testingGenetic findingsClinical managementCLINICAL TRIAL REGISTRY NAMEUnderlying causeGene panelTRIAL REGISTRY NAMEChronic kidney diseaseManagement of adultsAppropriate treatment strategyClinical care paradigmsPatient's medical historyClinical applicationAcademic medical centerClinical disease categoriesAdult patientsREGISTRY NAMEPrior diagnosisKidney diseaseMulticenter studyMedical historyTreatment strategiesMedical Center
2019
Revisiting racial differences in ESRD due to ADPKD in the United States
Murphy EL, Dai F, Blount KL, Droher ML, Liberti L, Crews DC, Dahl NK. Revisiting racial differences in ESRD due to ADPKD in the United States. BMC Nephrology 2019, 20: 55. PMID: 30764782, PMCID: PMC6376748, DOI: 10.1186/s12882-019-1241-1.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge DistributionAgedAged, 80 and overBlack or African AmericanChildChild, PreschoolDiabetic NephropathiesDisease ProgressionHumansHypertensionIncidenceInfantInfant, NewbornKidney Failure, ChronicMiddle AgedPolycystic Kidney, Autosomal DominantRetrospective StudiesSocioeconomic FactorsUnited StatesWhite PeopleYoung AdultConceptsNon-Hispanic blacksNon-Hispanic whitesNon-Hispanic white patientsUS Renal Data SystemIncidence of ESRDIncident ESRDWhite patientsFive-year age categoriesRetrospective cohort studyLarge vessel diseaseAdditional risk factorsAssociation of raceDominant polycystic kidney diseaseTwo-sample proportion testsPolycystic kidney diseaseTwo-sample t-testESRD onsetCohort studyADPKD populationKidney diseaseVessel diseaseBlack raceRisk factorsESRDHaenszel test
2016
Simple Renal Cysts as Markers of Thoracic Aortic Disease
Ziganshin BA, Theodoropoulos P, Salloum MN, Zaza KJ, Tranquilli M, Mojibian HR, Dahl NK, Fang H, Rizzo JA, Elefteriades JA. Simple Renal Cysts as Markers of Thoracic Aortic Disease. Journal Of The American Heart Association 2016, 5: e002248. PMID: 26746998, PMCID: PMC4859353, DOI: 10.1161/jaha.115.002248.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge DistributionAgedAged, 80 and overAortic Aneurysm, ThoracicAortic DissectionAortographyConnecticutFemaleHumansKidney Diseases, CysticMagnetic Resonance AngiographyMaleMiddle AgedPrevalenceRetrospective StudiesRisk FactorsSex DistributionTomography, X-Ray ComputedYoung AdultConceptsPrevalence of SRCThoracic aortic diseaseSimple renal cystsAortic aneurysmAortic dissectionControl groupAortic diseaseRenal cystsPresence of SRCType B aortic dissectionAortic disease patientsType B dissectionAbdominal computed tomographyB aortic dissectionAbdominal aortic aneurysmMagnetic resonance imagingB dissectionMale predominanceDisease patientsSilent diseaseClinical markersComputed tomographyPatientsAneurysmsResonance imaging
2014
CT Urography for the Diagnosis of Medullary Sponge Kidney
Koraishy FM, Ngo TT, Israel GM, Dahl NK. CT Urography for the Diagnosis of Medullary Sponge Kidney. American Journal Of Nephrology 2014, 39: 165-170. PMID: 24531190, DOI: 10.1159/000358496.Peer-Reviewed Original ResearchConceptsMedullary sponge kidneyCharacteristic radiologic findingsIntravenous pyelographyCT urographySponge kidneyRadiologic findingsMultidetector CTDiagnosis of MSKRenal acidification defectsUrinary tract infectionRisk of nephrolithiasisRenal stones clinicDose reduction protocolTerminal collecting ductsConventional intravenous pyelographyRenal collecting systemTubule dilatationMedullary nephrocalcinosisStone clinicTract infectionsSymptomatic nephrolithiasisMedullary cystsBone densityAcidification defectCollecting ducts