Electron Capture Dissociation for Structural Characterization of Multiply Charged Protein Cations
Zubarev R, Horn D, Fridriksson E, Kelleher N, Kruger N, Lewis M, Carpenter B, McLafferty F. Electron Capture Dissociation for Structural Characterization of Multiply Charged Protein Cations. Analytical Chemistry 2000, 72: 563-573. PMID: 10695143, DOI: 10.1021/ac990811p.Peer-Reviewed Original ResearchConceptsConventional MS/MS methodsElectron capture dissociationEven-electron ionsIon conversion efficiencyMS/MS methodCapture cross sectionCapture dissociationProtein cationsFragment ionsCAD spectraKinetic energy differenceStructural characterizationElectron captureEV differenceBackbone bondsIon cellsIonic chargeSecondary dissociationPotential wellMS methodCross sectionsIonsElectronsConversion efficiencyEnergy difference