2019
Immunoepidemiology of Selected Components of the Innate and Adaptive Immune Systems
Ruddle N, Kavathas P. Immunoepidemiology of Selected Components of the Innate and Adaptive Immune Systems. 2019, 111-125. DOI: 10.1007/978-3-030-25553-4_7.Peer-Reviewed Original ResearchKiller cell immunoglobulin-like receptorsPattern recognition receptorsT cell receptorMajor histocompatibility complexImmune systemSingle nucleotide polymorphismsImmunoglobulin-like receptorsAdaptive immune systemImmune responseRecognition receptorsPresence of polymorphismsCell receptorHistocompatibility complexGenetic polymorphismsReceptorsSelective survivalPolymorphismApparent effectMultiple microorganismsPregnancyChemokinesCytokinesImmunoepidemiologyInfectionInnateAdaptive Immunity: Antigen Recognition by T and B Lymphocytes
Kavathas P, Krause P, Ruddle N. Adaptive Immunity: Antigen Recognition by T and B Lymphocytes. 2019, 55-74. DOI: 10.1007/978-3-030-25553-4_4.ChaptersB cell receptorCell receptorMajor histocompatibility complexB lymphocytesKiller T cellsEffective immune responseVariety of antigensT cell receptors (TCRs) bindCentral toleranceT cellsImmune responseHLA proteinsAntigen recognitionHistocompatibility complexIntracellular pathogensCell surfaceReceptorsHLALymphocytesCorresponding antibodiesHost cellsAntibodiesIsotypesMHC systemDefense mechanisms
2016
Lymphotoxin
Ruddle N. Lymphotoxin. 2016, 466-475. DOI: 10.1016/b978-0-12-374279-7.10003-7.Peer-Reviewed Original ResearchTumor necrosis factorNFκB pathwayChronic inflammatory infiltrateAlternative NFκB pathwayMajor histocompatibility complexLymph nodesInflammatory infiltrateChemokine expressionChronic inflammationLymphoid organsNecrosis factorImmune responseCanonical NFκB pathwaySpecific antigenTNF receptorLymphotoxinLTβ receptorHistocompatibility complexTNF familyCulture supernatantsEmbryological developmentLymphocytesLTαCytotoxic activityReceptors