2020
Nonusefulness of Antithrombotic Therapy After Surgical Bioprosthetic Aortic Valve Replacement
Gryaznov AA, Saeyeldin A, Abdelbaky M, Zafar MA, Tanweer M, Papanikolaou D, Imran M, Li Y, Ziganshin BA, Elefteriades JA. Nonusefulness of Antithrombotic Therapy After Surgical Bioprosthetic Aortic Valve Replacement. The American Journal Of Cardiology 2020, 129: 71-78. PMID: 32605717, DOI: 10.1016/j.amjcard.2020.05.018.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnticoagulantsAortic ValveAortic Valve InsufficiencyAortic Valve StenosisAspirinAtrial FibrillationBicuspid Aortic Valve DiseaseBioprosthesisCoronary Artery DiseaseFactor Xa InhibitorsFemaleHeart Valve DiseasesHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHemorrhageHumansKaplan-Meier EstimateMaleMiddle AgedMortalityPlatelet Aggregation InhibitorsPostoperative CareProportional Hazards ModelsPurinergic P2Y Receptor AntagonistsStrokeThromboembolismWarfarinYoung AdultConceptsAortic valve replacementBiological aortic valve replacementAntithrombotic regimensValve replacementSurgical bioprosthetic aortic valve replacementCox proportional hazards regression modelSurgical aortic valve replacementBioprosthetic aortic valve replacementConsecutive adult patientsCoronary artery diseaseKaplan-Meier analysisIncidence of deathHazards regression modelsAntiplatelet groupAVR patientsRoutine anticoagulationAntithrombotic therapyCardiovascular eventsThromboembolic eventsAdult patientsAdverse eventsAnticoagulation groupArtery diseaseTreatment regimensTherapy group
2018
Antithrombotic Therapy after Bioprosthetic Aortic Valve Replacement: A Therapeutic Morass
Gryaznov AA, Saeyeldin A, Abdelbaky M, Zafar MA, Tanweer M, Imran M, Papanikolaou D, Erben Y, Zefirova J, Ziganshin BA, Elefteriades JA. Antithrombotic Therapy after Bioprosthetic Aortic Valve Replacement: A Therapeutic Morass. Cardiology 2018, 140: 213-221. PMID: 30138919, DOI: 10.1159/000490924.Peer-Reviewed Original ResearchConceptsAortic valve replacementValve replacementAortic stenosisSurgical aortic valve replacementBioprosthetic aortic valve replacementCommon valvular disorderImpact of anticoagulationSymptomatic aortic stenosisHigh-risk patientsValvular heart diseaseCommon pathologic conditionsAntithrombotic therapyMultiple comorbiditiesPerioperative complicationsRemote complicationsSurgical managementEndovascular interventionHeart diseaseValvular disordersBiological valvesLower riskEuropean guidelinesPathologic conditionsComplicationsStenosis