2018
Diabetes Mellitus: Is It Protective against Aneurysm? A Narrative Review
Patel K, Zafar MA, Ziganshin BA, Elefteriades JA. Diabetes Mellitus: Is It Protective against Aneurysm? A Narrative Review. Cardiology 2018, 141: 107-122. PMID: 30453299, DOI: 10.1159/000490373.Peer-Reviewed Original ResearchConceptsAbdominal aortic aneurysmAortic aneurysmDiabetic patientsAortic dissectionDipeptidyl peptidase-4 inhibitorsCommon antidiabetic medicationsPrevalence of TAAsPeptidase-4 inhibitorsAneurysm growth rateSmaller aneurysm diameterAortic wall stressRate of mortalityLow rupture ratesAntidiabetic medicationsAortic surgeryHospital stayDiabetic stateAortic growthAneurysm diameterAntidiabetic agentsDecreased lengthAneurysmsProtective roleRupture rateMatrix metalloproteinases
2016
Advanced Glycation End Products and its Soluble Receptors in the Pathogenesis of Thoracic Aortic Aneurysm
Prasad K, Sarkar A, Zafar MA, Shoker A, Moselhi HE, Tranquilli M, Ziganshin BA, Elefteriades JA. Advanced Glycation End Products and its Soluble Receptors in the Pathogenesis of Thoracic Aortic Aneurysm. Aorta 2016, 04: 1-10. PMID: 27766267, PMCID: PMC5068493, DOI: 10.12945/j.aorta.2015.15.018.Peer-Reviewed Original ResearchAdvanced glycation end productsEndogenous secretory RAGEThoracic aortic aneurysmGlycation end productsMatrix metalloproteinasesSerum sRAGEAortic aneurysmSoluble receptorFormation of TAALevels of AGEsPathogenesis of TAALevels of sRAGEAGE-RAGE axisLevels of cytokinesProduction of cytokinesRelease of cytokinesAGEs/Control subjectsRisk factorsStudy populationSRAGEBlood samplesMMP-2CytokinesELISA kit