Thoracic aortic aneurysm: unlocking the “silent killer” secrets
Saeyeldin AA, Velasquez CA, Mahmood SUB, Brownstein AJ, Zafar MA, Ziganshin BA, Elefteriades JA. Thoracic aortic aneurysm: unlocking the “silent killer” secrets. General Thoracic And Cardiovascular Surgery 2017, 67: 1-11. PMID: 29204794, DOI: 10.1007/s11748-017-0874-x.Peer-Reviewed Original ResearchConceptsAortic aneurysmAngiotensin receptor blockersFamilial patternBicuspid aortic valveAbdominal aortic aneurysmRisk of ruptureDifferent embryologic originsReceptor blockersBeta blockersType of repairThoracic aneurysmInflammatory disordersFemale sexSerum biomarkersAortic valveWorse outcomesEmbryologic originMedical treatmentEnzyme inhibitorsAneurysmsSilent killerIntracranial aneurysmsNatural historyOnly reliable methodPattern of inheritanceMedical management of aortic disease in Marfan syndrome.
Bin Mahmood SU, Velasquez CA, Zafar MA, Saeyeldin AA, Brownstein AJ, Ziganshin BA, Elefteriades JA, Mukherjee SK. Medical management of aortic disease in Marfan syndrome. Annals Of Cardiothoracic Surgery 2017, 6: 654-661. PMID: 29270377, PMCID: PMC5721117, DOI: 10.21037/acs.2017.11.09.Peer-Reviewed Original ResearchAngiotensin receptor blockersMedical managementMarfan syndromeMFS patientsThoracic aortic aneurysm diseaseDifferent medical regimensStandard of careAortic aneurysm diseaseNumerous pathophysiological effectsAortic dilatationReceptor blockersAortic diseaseMedical regimensCurrent guidelinesAneurysm diseaseCardiovascular organsΒ-blockersCurrent evidencePathophysiological effectsHereditary disorderPatientsSyndromeDiseaseRegimensManagement