Featured Publications
Bleeding avoidance strategies and percutaneous coronary intervention outcomes: A 10-year observation from a Japanese Multicenter Registry
Sawano M, Spertus J, Masoudi F, Rumsfeld J, Numasawa Y, Inohara T, Kennedy K, Ueda I, Miyata H, Fukuda K, Kohsaka S. Bleeding avoidance strategies and percutaneous coronary intervention outcomes: A 10-year observation from a Japanese Multicenter Registry. American Heart Journal 2021, 235: 113-124. PMID: 33472053, DOI: 10.1016/j.ahj.2021.01.010.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionTransfemoral approachTransradial approachNational Cardiovascular Data Registry CathPCI RegistryVascular closure device usePercutaneous coronary intervention outcomesMultivariable logistic regression analysisClosure device useConsecutive PCI patientsJapanese multicenter registryAdjusted odds ratioLogistic regression analysisPCI patientsCathPCI RegistryCoronary interventionMulticenter registryBleeding rateJapanese patientsOdds ratioRisk scoreLower riskPatientsUS populationCathPCIJapanese populationPerformance of the MAGGIC heart failure risk score and its modification with the addition of discharge natriuretic peptides
Sawano M, Shiraishi Y, Kohsaka S, Nagai T, Goda A, Mizuno A, Sujino Y, Nagatomo Y, Kohno T, Anzai T, Fukuda K, Yoshikawa T. Performance of the MAGGIC heart failure risk score and its modification with the addition of discharge natriuretic peptides. ESC Heart Failure 2018, 5: 610-619. PMID: 29520978, PMCID: PMC6073038, DOI: 10.1002/ehf2.12278.Peer-Reviewed Original ResearchConceptsMAGGIC scoreBNP levelsB-type natriuretic peptide levelsAcute Heart Failure registryChronic Heart Failure (MAGGIC) scoreConsecutive acute HF patientsHeart failure patient outcomesHeart Failure Risk ScoreMeta-Analysis Global GroupAcute HF patientsHeart Failure RegistryHeart failure scoreProspective multicentre registryIncremental prognostic valueNatriuretic peptide levelsHeart failure patientsMulticentre registryHF patientsFailure patientsYear mortalityNatriuretic peptidePatient mortalityPrognostic valueMean ageJapanese RegistryContemporary use and trends in percutaneous coronary intervention in Japan: an outline of the J-PCI registry
Sawano M, Yamaji K, Kohsaka S, Inohara T, Numasawa Y, Ando H, Iida O, Shinke T, Ishii H, Amano T. Contemporary use and trends in percutaneous coronary intervention in Japan: an outline of the J-PCI registry. Cardiovascular Intervention And Therapeutics 2020, 35: 218-226. PMID: 32440831, PMCID: PMC7295726, DOI: 10.1007/s12928-020-00669-z.Peer-Reviewed Original Research
2020
Association of decreasing hemoglobin levels with the incidence of acute kidney injury after percutaneous coronary intervention: a prospective multi-center study
Kuno T, Numasawa Y, Mikami T, Niimi N, Sawano M, Kodaira M, Suzuki M, Ueno K, Ueda I, Fukuda K, Kohsaka S. Association of decreasing hemoglobin levels with the incidence of acute kidney injury after percutaneous coronary intervention: a prospective multi-center study. Heart And Vessels 2020, 36: 330-336. PMID: 33034713, DOI: 10.1007/s00380-020-01706-w.Peer-Reviewed Original ResearchConceptsAcute kidney injuryPercutaneous coronary interventionRisk of AKIHemoglobin dropAKI incidenceKidney injuryCoronary interventionHemoglobin levelsProspective multi-center studySerum creatinine levelsMulti-center studyRelative decreaseConsecutive patientsCreatinine levelsIndependent predictorsRisk factorsHemoglobin changeHigh riskAbsolute decreaseLogistic regressionPatientsIncidenceHemoglobinInjuryDlElectrocardiographic ST-T Abnormities Are Associated With Stroke Risk in the REGARDS Study
Sawano M, Yuan Y, Kohsaka S, Inohara T, Suzuki T, Okamura T, Howard G, Howard V, Judd S, Soliman E, Cushman M. Electrocardiographic ST-T Abnormities Are Associated With Stroke Risk in the REGARDS Study. Stroke 2020, 51: 1100-1106. PMID: 32126939, PMCID: PMC7122793, DOI: 10.1161/strokeaha.119.028069.Peer-Reviewed Original ResearchConceptsIschemic strokeREGARDS studyMultivariable Cox proportional hazards regressionIncident coronary artery diseaseCox proportional hazards regressionAge-adjusted incidence ratesCalculate hazard ratiosFuture ischemic strokeIncident ischemic strokeMinnesota ECG ClassificationStroke risk factorsRisk of strokeCoronary artery diseaseProportional hazards regressionCoronary heart diseaseMinor ECG abnormalitiesNonspecific ST-segmentT-wave abnormalitiesIncident strokePrior strokeArtery diseaseHazard ratioStroke riskHazards regressionBaseline ECG
2019
Real-world use of intravascular ultrasound in Japan: a report from contemporary multicenter PCI registry
Kuno T, Numasawa Y, Sawano M, Abe T, Ueda I, Kodaira M, Suzuki M, Noma S, Nakamura I, Negishi K, Ishikawa S, Fukuda K, Kohsaka S. Real-world use of intravascular ultrasound in Japan: a report from contemporary multicenter PCI registry. Heart And Vessels 2019, 34: 1728-1739. PMID: 31129872, DOI: 10.1007/s00380-019-01427-9.Peer-Reviewed Original ResearchConceptsElective percutaneous coronary interventionPercutaneous coronary interventionEmergent percutaneous coronary interventionNon-IVUS groupPCI-related complicationsCoronary dissectionIntravascular ultrasoundIVUS usePCI registryMultivariate logistic regression analysisPlain old balloon angioplastyElective PCI patientsJapanese PCI registryMulticenter PCI registrySevere coronary dissectionMore comorbid conditionsClinical trial dataLogistic regression analysisLow event ratesIVUS groupPCI patientsCoronary interventionConsecutive patientsIndependent predictorsClinical outcomes
2018
Increasing mixed venous oxygen saturation is a predictor of improved renal function after balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension
Isobe S, Itabashi Y, Kawakami T, Kataoka M, Kohsaka S, Tsugu T, Kimura M, Sawano M, Katsuki T, Kohno T, Endo J, Murata M, Fukuda K. Increasing mixed venous oxygen saturation is a predictor of improved renal function after balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension. Heart And Vessels 2018, 34: 688-697. PMID: 30386916, DOI: 10.1007/s00380-018-1284-4.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngiographyAngioplasty, BalloonCardiac CatheterizationChronic DiseaseEchocardiographyFemaleFollow-Up StudiesGlomerular Filtration RateHumansHypertension, PulmonaryMaleMiddle AgedOxygenOxygen ConsumptionPrognosisPulmonary ArteryPulmonary EmbolismRetrospective StudiesVascular ResistanceVentricular Function, RightConceptsChronic thromboembolic pulmonary hypertensionBalloon pulmonary angioplastyInoperable chronic thromboembolic pulmonary hypertensionFinal BPARight heart functionThromboembolic pulmonary hypertensionRenal functionVenous oxygen saturationPulmonary hypertensionClinical characteristicsOxygen saturationHeart functionMean pulmonary arterial pressureMixed venous oxygen saturationPulmonary vascular resistancePulmonary arterial pressureGlomerular filtration ratePatients' clinical characteristicsBalloon pulmonaryImproved eGFRPulmonary angioplastyCardiac indexCTEPH patientsVascular resistanceArterial pressure
2016
Validation of the european SCORE risk chart in the healthy middle-aged Japanese
Sawano M, Kohsaka S, Okamura T, Inohara T, Sugiyama D, Watanabe M, Nakamura Y, Higashiyama A, Kadota A, Okud N, Murakami Y, Ohkubo T, Fujiyoshi A, Miura K, Okayama A, Ueshima H, Group F. Validation of the european SCORE risk chart in the healthy middle-aged Japanese. Atherosclerosis 2016, 252: 116-121. PMID: 27521900, DOI: 10.1016/j.atherosclerosis.2016.07.926.Peer-Reviewed Original ResearchConceptsCardiovascular death riskMiddle-aged JapaneseC-statisticDeath riskScore modelEuropean SCORE risk chartsOverall populationHarrel's c-statisticsSCORE risk chartsJapanese general populationHigh-risk populationGeneral Japanese populationCV deathRisk chartsGeneral populationEuropean SocietyJapanese populationDifferent ethnicitiesWomenPoor calibrationReasonable discriminationRiskMenPopulationTen years
2015
Validation of the Get With The Guideline–Heart Failure risk score in Japanese patients and the potential improvement of its discrimination ability by the inclusion of B-type natriuretic peptide level
Shiraishi Y, Kohsaka S, Abe T, Mizuno A, Goda A, Izumi Y, Yagawa M, Akita K, Sawano M, Inohara T, Takei M, Kohno T, Higuchi S, Yamazoe M, Mahara K, Fukuda K, Yoshikawa T, Investigators W. Validation of the Get With The Guideline–Heart Failure risk score in Japanese patients and the potential improvement of its discrimination ability by the inclusion of B-type natriuretic peptide level. American Heart Journal 2015, 171: 33-39. PMID: 26699598, DOI: 10.1016/j.ahj.2015.10.008.Peer-Reviewed Original ResearchConceptsB-type natriuretic peptide levelsGWTG-HF risk scoreAcute heart failureNatriuretic peptide levelsHospital mortalityRisk scorePeptide levelsAHF patientsC-statisticGuidelines-Heart Failure (GWTG-HF) risk scoreWest Tokyo Heart Failure registryChronic obstructive pulmonary diseaseBlood urea nitrogen levelsGWTG-HF scoreHeart Failure RegistryMulticenter cohort registryRisk score performanceObstructive pulmonary diseaseSystolic blood pressureUrea nitrogen levelsHosmer-Lemeshow statisticFuture risk modelsCohort registryBlood pressureHeart failure