2022
Conventional medical therapy in heart failure patients eligible for the PARADIGM-HF, DAPA-HF, and SHIFT trials
Shoji S, Kohsaka S, Shiraishi Y, Kohno T, Sawano M, Ikemura N, Niimi N, Nagatomo Y, Tanaka T, Takei M, Ono T, Sakamoto M, Nakano S, Nakamura I, Inoue S, Fukuda K, Yoshikawa T. Conventional medical therapy in heart failure patients eligible for the PARADIGM-HF, DAPA-HF, and SHIFT trials. International Journal Of Cardiology 2022, 359: 76-83. PMID: 35421518, DOI: 10.1016/j.ijcard.2022.04.020.Peer-Reviewed Original ResearchConceptsConventional medical therapyHF readmission ratesMedical therapy useMedical therapyLong-term outcomesEnrollment criteriaReadmission ratesTherapy useRecent trialsReduced ejection fractionHeart failure patientsHeart failure treatmentUse of BBsShift trialsDAPA-HFHF registryHFrEF patientsMulticenter registryPARADIGM-HFFailure patientsConsecutive patientsEjection fractionPatient subsetsPrescription ratesFailure treatment
2020
Independent and cumulative association of clinical and morphological heart failure with long-term outcome after percutaneous coronary intervention
Kimura M, Kohno T, Sawano M, Heidenreich P, Ueda I, Takahashi T, Matsubara T, Ueno K, Hayashida K, Yuasa S, Ohki T, Fukuda K, Kohsaka S. Independent and cumulative association of clinical and morphological heart failure with long-term outcome after percutaneous coronary intervention. Journal Of Cardiology 2020, 77: 41-47. PMID: 32888830, DOI: 10.1016/j.jjcc.2020.06.014.Peer-Reviewed Original ResearchMeSH KeywordsAgedCause of DeathFemaleHeart Disease Risk FactorsHeart FailureHospitalizationHumansIncidenceJapanMaleMiddle AgedPercutaneous Coronary InterventionPostoperative ComplicationsProportional Hazards ModelsRegistriesStrokeStroke VolumeTreatment OutcomeVentricular Dysfunction, LeftVentricular Function, LeftConceptsLeft ventricular systolic dysfunctionLeft ventricular ejection fractionMajor adverse cardiovascular eventsClinical heart failureNon-cardiac deathHeart failureLong-term outcomesHF hospitalizationIncidence of MACEAdverse long-term clinical outcomesLong-term clinical outcomesPercutaneous coronary intervention outcomesClinical HF symptomsMulticenter registry studyAdverse cardiovascular eventsCoronary artery bypassVentricular systolic dysfunctionAcute coronary syndromePercutaneous coronary interventionVentricular ejection fractionPost-procedural outcomesCause deathArtery bypassCardiovascular eventsCoronary syndrome
2018
Validation and Recalibration of Seattle Heart Failure Model in Japanese Acute Heart Failure Patients
Shiraishi Y, Kohsaka S, Nagai T, Goda A, Mizuno A, Nagatomo Y, Sujino Y, Fukuoka R, Sawano M, Kohno T, Fukuda K, Anzai T, Shadman R, Dardas T, Levy W, Yoshikawa T. Validation and Recalibration of Seattle Heart Failure Model in Japanese Acute Heart Failure Patients. Journal Of Cardiac Failure 2018, 25: 561-567. PMID: 30099192, DOI: 10.1016/j.cardfail.2018.07.463.Peer-Reviewed Original ResearchConceptsSeattle Heart Failure ModelHeart failure patientsHF patientsHeart failure modelHFrEF patientsHFpEF patientsEjection fractionFailure patientsAcute heart failure patientsAcute HF patientsConventional clinical variablesJapanese HF patientsReduced ejection fractionPrecise risk stratificationAcute decompensationHeart failureHospital admissionNational CerebralRisk stratificationClinical variablesC-statisticHeart failure databaseModest discriminationPatientsMedical resources
2017
Current use of guideline-based medical therapy in elderly patients admitted with acute heart failure with reduced ejection fraction and its impact on event-free survival
Akita K, Kohno T, Kohsaka S, Shiraishi Y, Nagatomo Y, Izumi Y, Goda A, Mizuno A, Sawano M, Inohara T, Fukuda K, Yoshikawa T, Investigators W. Current use of guideline-based medical therapy in elderly patients admitted with acute heart failure with reduced ejection fraction and its impact on event-free survival. International Journal Of Cardiology 2017, 235: 162-168. PMID: 28259550, DOI: 10.1016/j.ijcard.2017.02.070.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAge FactorsAgedAged, 80 and overAngiotensin-Converting Enzyme InhibitorsFemaleHeart FailureHumansJapanMaleMedication Therapy ManagementMiddle AgedNeeds AssessmentOutcome and Process Assessment, Health CarePatient DischargePatient ReadmissionPractice Guidelines as TopicStroke VolumeVentricular Dysfunction, LeftConceptsGuideline-based medical therapyAcute heart failureReduced ejection fractionElderly patientsHeart failureEjection fractionHF readmissionMedical therapyWest Tokyo Heart Failure registryConsecutive acute HF patientsYounger groupAcute HF patientsElderly HFrEF patientsHeart Failure RegistryEvent-free survivalMulti-center registryIdeal therapeutic approachHF rehospitalizationHFrEF patientsHF patientsCurrent useCardiac deathComposite endpointPrescription ratesPoor outcome
2015
Effect of Estimated Plasma Volume Reduction on Renal Function for Acute Heart Failure Differs Between Patients With Preserved and Reduced Ejection Fraction
Takei M, Kohsaka S, Shiraishi Y, Goda A, Izumi Y, Yagawa M, Mizuno A, Sawano M, Inohara T, Kohno T, Fukuda K, Yoshikawa T. Effect of Estimated Plasma Volume Reduction on Renal Function for Acute Heart Failure Differs Between Patients With Preserved and Reduced Ejection Fraction. Circulation Heart Failure 2015, 8: 527-532. PMID: 25737498, DOI: 10.1161/circheartfailure.114.001734.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdministration, IntravenousAgedAged, 80 and overChi-Square DistributionDisease ProgressionDiuresisDiureticsFemaleHeart FailureHumansIdeal Body WeightKidneyLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPlasma VolumeRegistriesRenal Insufficiency, ChronicRetrospective StudiesRisk FactorsStroke VolumeTime FactorsTokyoTreatment OutcomeVentricular Function, LeftConceptsPlasma volume reductionAcute heart failureHeart failureRenal functionEjection fractionBody weightWest Tokyo Heart Failure registryAcute heart failure patientsReduced ejection fraction cohortReduced ejection fraction groupEjection fraction groupHeart Failure RegistryReduced ejection fractionHistory of hypertensionGlomerular filtration rateHeart failure patientsIdeal body weightSubject's body weightVolume reductionHFpEF cohortIntravenous diureticsFailure patientsHemodynamic effectsDiabetes mellitusKidney function