Featured Publications
Bleeding avoidance strategies and percutaneous coronary intervention outcomes: A 10-year observation from a Japanese Multicenter Registry
Sawano M, Spertus J, Masoudi F, Rumsfeld J, Numasawa Y, Inohara T, Kennedy K, Ueda I, Miyata H, Fukuda K, Kohsaka S. Bleeding avoidance strategies and percutaneous coronary intervention outcomes: A 10-year observation from a Japanese Multicenter Registry. American Heart Journal 2021, 235: 113-124. PMID: 33472053, DOI: 10.1016/j.ahj.2021.01.010.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionTransfemoral approachTransradial approachNational Cardiovascular Data Registry CathPCI RegistryVascular closure device usePercutaneous coronary intervention outcomesMultivariable logistic regression analysisClosure device useConsecutive PCI patientsJapanese multicenter registryAdjusted odds ratioLogistic regression analysisPCI patientsCathPCI RegistryCoronary interventionMulticenter registryBleeding rateJapanese patientsOdds ratioRisk scoreLower riskPatientsUS populationCathPCIJapanese population
2021
Evidence‐to‐Practice Gap for Preventing Procedure‐Related Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Intervention
Shoji S, Sawano M, Sandhu A, Heidenreich P, Shiraishi Y, Noma S, Suzuki M, Numasawa Y, Fukuda K, Kohsaka S. Evidence‐to‐Practice Gap for Preventing Procedure‐Related Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Intervention. Journal Of The American Heart Association 2021, 10: e020047. PMID: 34310187, PMCID: PMC8475676, DOI: 10.1161/jaha.120.020047.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAgedAged, 80 and overClinical Decision-MakingContrast MediaDatabases, FactualEvidence-Based MedicineFemaleHumansIncidenceJapanKidneyKidney Function TestsMaleMiddle AgedPercutaneous Coronary InterventionProfessional Practice GapsProtective FactorsQuality ImprovementQuality Indicators, Health CareRadiography, InterventionalRetrospective StudiesRisk AssessmentRisk FactorsTreatment OutcomeConceptsAcute kidney injuryPercutaneous coronary interventionAKI risk scoreBaseline renal functionContrast volumeCoronary interventionRisk scoreAKI riskKidney injuryRenal functionAcute coronary syndrome presentationBackground Acute kidney injuryIntra-aortic balloon pumpMultivariable linear regression analysisContrast volume usagePreprocedural risk assessmentChronic kidney diseaseAvailable risk scoresCommon complicationBalloon pumpHeart failureSusceptible patientsOverall incidenceSyndrome presentationKidney disease
2020
Guideline-Based Medications for Older Adults Discharged after Percutaneous Coronary Intervention in a Suburban City of Japan: A Cohort Study Using Claims Data
Shimada K, Hamada S, Sawano M, Yamamoto H, Yoshie S, Iijima K, Miyata H. Guideline-Based Medications for Older Adults Discharged after Percutaneous Coronary Intervention in a Suburban City of Japan: A Cohort Study Using Claims Data. The Tohoku Journal Of Experimental Medicine 2020, 252: 143-152. PMID: 33028759, DOI: 10.1620/tjem.252.143.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAgedAged, 80 and overAngiotensin Receptor AntagonistsAngiotensin-Converting Enzyme InhibitorsFemaleGeriatricsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsInsurance Claim ReviewJapanMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionOdds RatioPatient DischargePercutaneous Coronary InterventionPractice Guidelines as TopicRetrospective StudiesSecondary PreventionConceptsPercutaneous coronary interventionGuideline-based medicationsSecondary preventionΒ-blockersCohort studyCoronary interventionPrescription ratesClaims dataMultivariable logistic regression analysisOlder groupOlder adultsPrescription of antiplateletACEI/ARBRetrospective cohort studyAssociation of ageLogistic regression analysisCardiovascular eventsReceptor blockersAdjusted analysisBetter prognosisEnzyme inhibitorsMedicationsCommunity settingsStatinsPreventionIschemic and Bleeding Events Among Patients With Acute Coronary Syndrome Associated With Low-Dose Prasugrel vs Standard-Dose Clopidogrel Treatment
Shoji S, Sawano M, Sandhu A, Heidenreich P, Shiraishi Y, Ikemura N, Ueno K, Suzuki M, Numasawa Y, Fukuda K, Kohsaka S. Ischemic and Bleeding Events Among Patients With Acute Coronary Syndrome Associated With Low-Dose Prasugrel vs Standard-Dose Clopidogrel Treatment. JAMA Network Open 2020, 3: e202004. PMID: 32239221, PMCID: PMC7118520, DOI: 10.1001/jamanetworkopen.2020.2004.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAged, 80 and overAspirinBrain IschemiaCase-Control StudiesClopidogrelDeathDrug Therapy, CombinationFemaleHemorrhageHumansJapanMaleMiddle AgedMyocardial InfarctionPercutaneous Coronary InterventionPlatelet Aggregation InhibitorsPrasugrel HydrochlorideRegistriesRenal Insufficiency, ChronicRetrospective StudiesRisk AssessmentStrokeConceptsLow-dose prasugrelPercutaneous coronary interventionPrimary ischemic eventsAcute coronary syndromeBleeding eventsIschemic eventsCoronary syndromeST-segment elevation myocardial infarctionAcute Coronary Syndrome AssociatedPropensity score-matched analysisHigh-bleeding riskStandard-dose clopidogrelChronic kidney diseaseElevation myocardial infarctionPresent cohort studyShort-term outcomesEast Asian patientsReal-world outcomesPrasugrel treatmentClopidogrel administrationP2Y12 inhibitorsBaseline characteristicsClopidogrel treatmentCohort studyCoronary intervention
2019
Outcomes of acute coronary syndrome patients with concurrent extra-cardiac vascular disease in the era of transradial coronary intervention: A retrospective multicenter cohort study
Kodaira M, Sawano M, Kuno T, Numasawa Y, Noma S, Suzuki M, Imaeda S, Ueda I, Fukuda K, Kohsaka S. Outcomes of acute coronary syndrome patients with concurrent extra-cardiac vascular disease in the era of transradial coronary intervention: A retrospective multicenter cohort study. PLOS ONE 2019, 14: e0223215. PMID: 31618228, PMCID: PMC6795465, DOI: 10.1371/journal.pone.0223215.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAged, 80 and overCerebrovascular DisordersFemaleHospital MortalityHumansIncidenceMaleMiddle AgedPercutaneous Coronary InterventionPeripheral Vascular DiseasesPostoperative HemorrhageRadial ArteryRegistriesRetrospective StudiesRisk FactorsSeverity of Illness IndexTreatment OutcomeConceptsTransradial coronary interventionAcute coronary syndromePeripheral arterial diseaseCerebrovascular diseaseCoronary interventionVascular diseaseRetrospective multicenter cohort studyAcute coronary syndrome patientsPercutaneous coronary intervention registryMulticenter cohort studyCoronary syndrome patientsCoronary Intervention RegistryIncidence of deathCoronary syndromeCohort studyIntervention RegistryArterial diseaseAdverse outcomesRisk factorsPatient outcomesAccess siteSyndrome patientsHigh riskComplicationsPatients
2018
An overview of percutaneous coronary intervention in dialysis patients: Insights from a Japanese nationwide registry
Numasawa Y, Inohara T, Ishii H, Yamaji K, Hirano K, Kohsaka S, Sawano M, Kuno T, Kodaira M, Uemura S, Kadota K, Amano T, Nakamura M, Investigators O. An overview of percutaneous coronary intervention in dialysis patients: Insights from a Japanese nationwide registry. Catheterization And Cardiovascular Interventions 2018, 94: e1-e8. PMID: 30467967, DOI: 10.1002/ccd.27986.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionJapanese nationwide registryDialysis patientsHospital mortalityNondialysis patientsCoronary interventionNationwide registryACS cohortHeart failureAdverse outcomesAcute heart failureMore comorbiditiesCardiogenic shockHospital outcomesBlood transfusionClinical trialsFemale genderPCI casesPatientsJapanese hospitalsGreater riskMortalityComplicationsRegistryRiskIncreasing mixed venous oxygen saturation is a predictor of improved renal function after balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension
Isobe S, Itabashi Y, Kawakami T, Kataoka M, Kohsaka S, Tsugu T, Kimura M, Sawano M, Katsuki T, Kohno T, Endo J, Murata M, Fukuda K. Increasing mixed venous oxygen saturation is a predictor of improved renal function after balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension. Heart And Vessels 2018, 34: 688-697. PMID: 30386916, DOI: 10.1007/s00380-018-1284-4.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngiographyAngioplasty, BalloonCardiac CatheterizationChronic DiseaseEchocardiographyFemaleFollow-Up StudiesGlomerular Filtration RateHumansHypertension, PulmonaryMaleMiddle AgedOxygenOxygen ConsumptionPrognosisPulmonary ArteryPulmonary EmbolismRetrospective StudiesVascular ResistanceVentricular Function, RightConceptsChronic thromboembolic pulmonary hypertensionBalloon pulmonary angioplastyInoperable chronic thromboembolic pulmonary hypertensionFinal BPARight heart functionThromboembolic pulmonary hypertensionRenal functionVenous oxygen saturationPulmonary hypertensionClinical characteristicsOxygen saturationHeart functionMean pulmonary arterial pressureMixed venous oxygen saturationPulmonary vascular resistancePulmonary arterial pressureGlomerular filtration ratePatients' clinical characteristicsBalloon pulmonaryImproved eGFRPulmonary angioplastyCardiac indexCTEPH patientsVascular resistanceArterial pressure
2015
Effect of Estimated Plasma Volume Reduction on Renal Function for Acute Heart Failure Differs Between Patients With Preserved and Reduced Ejection Fraction
Takei M, Kohsaka S, Shiraishi Y, Goda A, Izumi Y, Yagawa M, Mizuno A, Sawano M, Inohara T, Kohno T, Fukuda K, Yoshikawa T. Effect of Estimated Plasma Volume Reduction on Renal Function for Acute Heart Failure Differs Between Patients With Preserved and Reduced Ejection Fraction. Circulation Heart Failure 2015, 8: 527-532. PMID: 25737498, DOI: 10.1161/circheartfailure.114.001734.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdministration, IntravenousAgedAged, 80 and overChi-Square DistributionDisease ProgressionDiuresisDiureticsFemaleHeart FailureHumansIdeal Body WeightKidneyLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPlasma VolumeRegistriesRenal Insufficiency, ChronicRetrospective StudiesRisk FactorsStroke VolumeTime FactorsTokyoTreatment OutcomeVentricular Function, LeftConceptsPlasma volume reductionAcute heart failureHeart failureRenal functionEjection fractionBody weightWest Tokyo Heart Failure registryAcute heart failure patientsReduced ejection fraction cohortReduced ejection fraction groupEjection fraction groupHeart Failure RegistryReduced ejection fractionHistory of hypertensionGlomerular filtration rateHeart failure patientsIdeal body weightSubject's body weightVolume reductionHFpEF cohortIntravenous diureticsFailure patientsHemodynamic effectsDiabetes mellitusKidney function