2024
A Novel Risk Score for Major Bleeding in Japanese Patients with Non-Valvular Atrial Fibrillation: The J-RISK AF Study
Akao M, Tomita H, Nakai M, Kodani E, Suzuki S, Hayashi K, Sawano M, Goya M, Yamashita T, Fukuda K, Tsuda T, Isobe M, Toyoda K, Miyamoto Y, Okamura T, Sasahara Y, Okumura K, Group O. A Novel Risk Score for Major Bleeding in Japanese Patients with Non-Valvular Atrial Fibrillation: The J-RISK AF Study. Journal Of Atherosclerosis And Thrombosis 2024, 31: 1591-1606. PMID: 38811233, PMCID: PMC11537787, DOI: 10.5551/jat.64842.Peer-Reviewed Original ResearchNon-valvular atrial fibrillationOral anticoagulantsRisk stratification systemJapanese patientsHAS-BLEDAtrial fibrillationNon-valvular atrial fibrillation patientsMultivariate Cox proportional hazards analysisConcomitant antiplatelet agentsAF studyCox proportional hazards analysisRisk scoreStratification systemBleeding risk stratificationFollow-up periodNovel risk scoreProportional hazards analysisRisk of ischemic strokeAF RegistryNon-valvularBleeding historyMajor bleedingRisk stratificationAntiplatelet agentsBleeding
2023
One‐year outcomes of patients undergoing percutaneous coronary intervention with the revived directional coronary atherectomy catheter: Insights from the J‐PCI OUTCOME registry
Numasawa Y, Sawano M, Ishii H, Kohsaka S, Kikuta Y, Matoba T, Amano T, Kozuma K, Investigators T. One‐year outcomes of patients undergoing percutaneous coronary intervention with the revived directional coronary atherectomy catheter: Insights from the J‐PCI OUTCOME registry. Catheterization And Cardiovascular Interventions 2023, 102: 1229-1237. PMID: 37943854, DOI: 10.1002/ccd.30895.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsDirectional coronary atherectomyPercutaneous coronary interventionStable coronary artery diseaseOne-year outcomesCoronary artery diseaseMajor bleedingCoronary interventionUnstable anginaArtery diseaseDCA groupContemporary real-world practiceDrug-coated balloon angioplastyOne-year clinical outcomesJapanese nationwide registryNonfatal major bleedingAdverse cardiovascular eventsCardiovascular deathCardiovascular eventsCause mortalityMidterm outcomesBaseline characteristicsCardiovascular mortalityCoronary atherectomyNationwide registry
2022
Impact of baseline blood pressure on adverse outcomes in Japanese patients with non-valvular atrial fibrillation: the J-RISK AF
Kodani E, Tomita H, Nakai M, Akao M, Suzuki S, Hayashi K, Sawano M, Goya M, Yamashita T, Fukuda K, Ogawa H, Tsuda T, Isobe M, Toyoda K, Miyamoto Y, Miyata H, Okamura T, Sasahara Y, Okumura K, Group F. Impact of baseline blood pressure on adverse outcomes in Japanese patients with non-valvular atrial fibrillation: the J-RISK AF. European Heart Journal Open 2022, 2: oeac081. PMID: 36583077, PMCID: PMC9793850, DOI: 10.1093/ehjopen/oeac081.Peer-Reviewed Original ResearchSystolic baseline blood pressureBaseline blood pressureAtrial fibrillationMajor bleedingHazard ratioAF RegistryJapanese patientsCardiovascular deathIschemic strokeBlood pressureAdverse outcomesBaseline systolic BPNon-valvular AF patientsNon-valvular atrial fibrillationFushimi AF RegistryJ-RHYTHM RegistryIndependent risk factorBaseline BP valuesLarge-scale cohortCause deathAdverse eventsCardiovascular mortalityAF patientsPooled analysisRisk factorsOne-year outcome after percutaneous coronary intervention in nonagenarians: Insights from the J-PCI OUTCOME registry
Otowa K, Kohsaka S, Sawano M, Matsuura S, Chikata A, Maruyama M, Usuda K, Watanabe T, Ishii H, Amano T, Nakamura M, Ikari Y. One-year outcome after percutaneous coronary intervention in nonagenarians: Insights from the J-PCI OUTCOME registry. American Heart Journal 2022, 246: 105-116. PMID: 35016854, DOI: 10.1016/j.ahj.2022.01.004.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionAdverse cardiovascular eventsLong-term outcomesCardiovascular eventsNonagenarian patientsCardiovascular mortalityCoronary interventionOutcomes RegistryMajor adverse cardiovascular eventsCV death rateMajor bleeding eventsOne-year outcomesNationwide registration systemPatient-level dataLong-term survivalYears of ageMultivariate regression analysisBleeding eventsCardiogenic shockMajor bleedingOral anticoagulantsAdverse eventsElder patientsCardiac arrestLesion characteristics
2021
Female sex as an independent predictor of high bleeding risk among East Asian percutaneous coronary intervention patients: A sex difference analysis
Kodaira M, Sawano M, Tanaka M, Kuno T, Numasawa Y, Ueda I, Fukuda K, Kohsaka S. Female sex as an independent predictor of high bleeding risk among East Asian percutaneous coronary intervention patients: A sex difference analysis. Journal Of Cardiology 2021, 78: 431-438. PMID: 34172350, DOI: 10.1016/j.jjcc.2021.05.016.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionAcute coronary syndromeFine-Gray modelPrimary outcomeFemale sexPercutaneous coronary intervention patientsLower body mass indexEtiology of readmissionMulticenter PCI registryPrevious heart failureUnadjusted readmission ratesAdjusted hazard ratioHigh bleeding riskBody mass indexLong-term outcomesCox regression modelACS survivorsCumulative incidence functionMajor bleedingMore comorbiditiesBleeding riskCoronary syndromeIntervention patientsPCI registryCoronary intervention