Featured Publications
Sex Difference in Outcomes of Acute Myocardial Infarction in Young Patients
Sawano M, Lu Y, Caraballo C, Mahajan S, Dreyer R, Lichtman J, D'Onofrio G, Spatz E, Khera R, Onuma O, Murugiah K, Spertus J, Krumholz H. Sex Difference in Outcomes of Acute Myocardial Infarction in Young Patients. Journal Of The American College Of Cardiology 2023, 81: 1797-1806. PMID: 37137590, DOI: 10.1016/j.jacc.2023.03.383.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionNoncardiac hospitalizationsSubdistribution HRYounger patientsMyocardial infarctionSex differencesYoung womenCause-specific hospitalizationsCause of hospitalizationWorse health statusSignificant sex disparityNoncardiovascular hospitalizationsVIRGO StudyIndex episodeAdverse outcomesIncidence rateHospitalizationHigh riskSex disparitiesHealth statusPatientsU.S. hospitalsWomenInfarctionOutcomes
2023
Ischemic and Bleeding Outcomes in Patients Who Underwent Percutaneous Coronary Intervention With Chronic Kidney Disease or Dialysis (from a Japanese Nationwide Registry)
Tobe A, Sawano M, Kohsaka S, Ishii H, Tanaka A, Numasawa Y, Amano T, Nakamura M, Ikari Y, Murohara T. Ischemic and Bleeding Outcomes in Patients Who Underwent Percutaneous Coronary Intervention With Chronic Kidney Disease or Dialysis (from a Japanese Nationwide Registry). The American Journal Of Cardiology 2023, 195: 37-44. PMID: 37004333, DOI: 10.1016/j.amjcard.2023.02.027.Peer-Reviewed Original ResearchConceptsChronic kidney diseasePercutaneous coronary interventionPresence of CKDCKD stages 1Ischemic eventsAdjustment of covariatesHigh riskPCI registryCoronary interventionKidney diseaseNew-generation drug-eluting stent implantationDrug-eluting stent implantationUnderwent Percutaneous Coronary InterventionCKD stage 3Stage 1Bleeding eventsBleeding outcomesDialysis groupOral anticoagulantsCKD 3Renal functionStent implantationIncidence ratePatientsCare delivery
2021
One-Year Outcome After Percutaneous Coronary Intervention for Acute Coronary Syndrome ― An Analysis of 20,042 Patients From a Japanese Nationwide Registry ―
Sawano M, Kohsaka S, Ishii H, Numasawa Y, Yamaji K, Inohara T, Amano T, Ikari Y, Nakamura M. One-Year Outcome After Percutaneous Coronary Intervention for Acute Coronary Syndrome ― An Analysis of 20,042 Patients From a Japanese Nationwide Registry ―. Circulation Journal 2021, 85: 1756-1767. PMID: 34162778, DOI: 10.1253/circj.cj-21-0098.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionST-elevation myocardial infarctionHeart failureHospital survivorsCoronary interventionIschemic strokeUnstable anginaMyocardial infarctionHigh riskAcute myocardial infarction populationNon-fatal ischemic strokeLate adverse cardiac eventsJapanese nationwide cohortJapanese nationwide registryNon-cardiac deathAcute heart failureAdverse cardiac eventsAcute coronary syndromeHeart failure eventsOne-year outcomesElevation myocardial infarctionSudden cardiac deathMyocardial infarction populationQuality of careACS patients
2020
Association of decreasing hemoglobin levels with the incidence of acute kidney injury after percutaneous coronary intervention: a prospective multi-center study
Kuno T, Numasawa Y, Mikami T, Niimi N, Sawano M, Kodaira M, Suzuki M, Ueno K, Ueda I, Fukuda K, Kohsaka S. Association of decreasing hemoglobin levels with the incidence of acute kidney injury after percutaneous coronary intervention: a prospective multi-center study. Heart And Vessels 2020, 36: 330-336. PMID: 33034713, DOI: 10.1007/s00380-020-01706-w.Peer-Reviewed Original ResearchConceptsAcute kidney injuryPercutaneous coronary interventionRisk of AKIHemoglobin dropAKI incidenceKidney injuryCoronary interventionHemoglobin levelsProspective multi-center studySerum creatinine levelsMulti-center studyRelative decreaseConsecutive patientsCreatinine levelsIndependent predictorsRisk factorsHemoglobin changeHigh riskAbsolute decreaseLogistic regressionPatientsIncidenceHemoglobinInjuryDl
2019
In-hospital outcome in patients presenting with acute coronary syndrome with left main coronary artery disease: A report from Japanese prospective multicenter percutaneous coronary intervention registry
Tani H, Sawano M, Numasawa Y, Kobayashi Y, Suzuki M, Noma S, Shiraishi Y, Ueda I, Fukuda K, Kohsaka S. In-hospital outcome in patients presenting with acute coronary syndrome with left main coronary artery disease: A report from Japanese prospective multicenter percutaneous coronary intervention registry. Journal Of Cardiology 2019, 75: 635-640. PMID: 31899113, DOI: 10.1016/j.jjcc.2019.11.006.Peer-Reviewed Original ResearchConceptsAcute coronary syndromePercutaneous coronary interventionCardiogenic shockMortality rateACS patientsHospital mortalityCoronary syndromeHospital outcomesHigh riskLeft main coronary artery diseaseMain coronary artery diseasePresence of CSST-elevation myocardial infarctionPercutaneous coronary intervention registryContemporary risk modelsCoronary lesion characteristicsLeft main diseaseCoronary artery bypassHospital mortality rateDe novo patientsElevation myocardial infarctionCoronary artery diseaseCoronary Intervention RegistryShort-term outcomesKey clinical characteristicsOutcomes of acute coronary syndrome patients with concurrent extra-cardiac vascular disease in the era of transradial coronary intervention: A retrospective multicenter cohort study
Kodaira M, Sawano M, Kuno T, Numasawa Y, Noma S, Suzuki M, Imaeda S, Ueda I, Fukuda K, Kohsaka S. Outcomes of acute coronary syndrome patients with concurrent extra-cardiac vascular disease in the era of transradial coronary intervention: A retrospective multicenter cohort study. PLOS ONE 2019, 14: e0223215. PMID: 31618228, PMCID: PMC6795465, DOI: 10.1371/journal.pone.0223215.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAged, 80 and overCerebrovascular DisordersFemaleHospital MortalityHumansIncidenceMaleMiddle AgedPercutaneous Coronary InterventionPeripheral Vascular DiseasesPostoperative HemorrhageRadial ArteryRegistriesRetrospective StudiesRisk FactorsSeverity of Illness IndexTreatment OutcomeConceptsTransradial coronary interventionAcute coronary syndromePeripheral arterial diseaseCerebrovascular diseaseCoronary interventionVascular diseaseRetrospective multicenter cohort studyAcute coronary syndrome patientsPercutaneous coronary intervention registryMulticenter cohort studyCoronary syndrome patientsCoronary Intervention RegistryIncidence of deathCoronary syndromeCohort studyIntervention RegistryArterial diseaseAdverse outcomesRisk factorsPatient outcomesAccess siteSyndrome patientsHigh riskComplicationsPatients
2017
Patterns of statin non-prescription in patients with established coronary artery disease: A report from a contemporary multicenter Japanese PCI registry
Sawano M, Kohsaka S, Abe T, Inohara T, Maekawa Y, Ueda I, Sueyoshi K, Suzuki M, Noma S, Numasawa Y, Miyata H, Fukuda K, Smolderen KG, Spertus JA. Patterns of statin non-prescription in patients with established coronary artery disease: A report from a contemporary multicenter Japanese PCI registry. PLOS ONE 2017, 12: e0182687. PMID: 28817616, PMCID: PMC5560610, DOI: 10.1371/journal.pone.0182687.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseCoronary artery diseasePCI patientsStatin therapyArtery diseaseKidney diseaseHierarchical multivariable logistic regression analysisMultivariable logistic regression analysisPercutaneous coronary intervention registryJapanese PCI registryStatin prescription patternsCoronary Intervention RegistryLow-intensity statinsLogistic regression analysisCardiovascular eventsPCI registryIntervention RegistryPatient characteristicsPrescription patternsReal-world practiceStudy registryEffective medicationsHigh riskPatientsHigher age
2016
Independent Prognostic Value of Single and Multiple Non-Specific 12-Lead Electrocardiographic Findings for Long-Term Cardiovascular Outcomes: A Prospective Cohort Study
Sawano M, Kohsaka S, Okamura T, Inohara T, Sugiyama D, Shiraishi Y, Watanabe M, Nakamura Y, Higashiyama A, Kadota A, Okuda N, Murakami Y, Ohkubo T, Fujiyoshi A, Miura K, Okayama A, Ueshima H, . Independent Prognostic Value of Single and Multiple Non-Specific 12-Lead Electrocardiographic Findings for Long-Term Cardiovascular Outcomes: A Prospective Cohort Study. PLOS ONE 2016, 11: e0157563. PMID: 27362562, PMCID: PMC4928789, DOI: 10.1371/journal.pone.0157563.Peer-Reviewed Original ResearchConceptsFramingham risk scoreCardiovascular deathRisk chartsRisk scoreCohort studyLong-term cardiovascular deathLong-term prognostic effectLong-term cardiovascular outcomesProspective cohort studyIndependent prognostic valueLongitudinal cohort studyRisk stratification systemCause deathCardiovascular outcomesCoronary deathElectrocardiogram findingsHazard ratioPrognostic impactStroke deathsElectrocardiographic findingsPrognostic effectPrognostic valueHealthy menRepolarization abnormalitiesHigh risk