Featured Publications
Performance of the MAGGIC heart failure risk score and its modification with the addition of discharge natriuretic peptides
Sawano M, Shiraishi Y, Kohsaka S, Nagai T, Goda A, Mizuno A, Sujino Y, Nagatomo Y, Kohno T, Anzai T, Fukuda K, Yoshikawa T. Performance of the MAGGIC heart failure risk score and its modification with the addition of discharge natriuretic peptides. ESC Heart Failure 2018, 5: 610-619. PMID: 29520978, PMCID: PMC6073038, DOI: 10.1002/ehf2.12278.Peer-Reviewed Original ResearchConceptsMAGGIC scoreBNP levelsB-type natriuretic peptide levelsAcute Heart Failure registryChronic Heart Failure (MAGGIC) scoreConsecutive acute HF patientsHeart failure patient outcomesHeart Failure Risk ScoreMeta-Analysis Global GroupAcute HF patientsHeart Failure RegistryHeart failure scoreProspective multicentre registryIncremental prognostic valueNatriuretic peptide levelsHeart failure patientsMulticentre registryHF patientsFailure patientsYear mortalityNatriuretic peptidePatient mortalityPrognostic valueMean ageJapanese Registry
2022
Conventional medical therapy in heart failure patients eligible for the PARADIGM-HF, DAPA-HF, and SHIFT trials
Shoji S, Kohsaka S, Shiraishi Y, Kohno T, Sawano M, Ikemura N, Niimi N, Nagatomo Y, Tanaka T, Takei M, Ono T, Sakamoto M, Nakano S, Nakamura I, Inoue S, Fukuda K, Yoshikawa T. Conventional medical therapy in heart failure patients eligible for the PARADIGM-HF, DAPA-HF, and SHIFT trials. International Journal Of Cardiology 2022, 359: 76-83. PMID: 35421518, DOI: 10.1016/j.ijcard.2022.04.020.Peer-Reviewed Original ResearchConceptsConventional medical therapyHF readmission ratesMedical therapy useMedical therapyLong-term outcomesEnrollment criteriaReadmission ratesTherapy useRecent trialsReduced ejection fractionHeart failure patientsHeart failure treatmentUse of BBsShift trialsDAPA-HFHF registryHFrEF patientsMulticenter registryPARADIGM-HFFailure patientsConsecutive patientsEjection fractionPatient subsetsPrescription ratesFailure treatment
2021
Sudden cardiac death after acute decompensation in heart failure patients: implications of discharge haemoglobin levels
Fukuoka R, Kohsaka S, Shiraishi Y, Sawano M, Abe T, Levy W, Nagatomo Y, Nishihata Y, Goda A, Kohno T, Kawamura A, Fukuda K, Yoshikawa T. Sudden cardiac death after acute decompensation in heart failure patients: implications of discharge haemoglobin levels. ESC Heart Failure 2021, 8: 3917-3928. PMID: 34323007, PMCID: PMC8497203, DOI: 10.1002/ehf2.13414.Peer-Reviewed Original ResearchConceptsSudden cardiac deathPump failure deathAcute HF patientsDischarge Hb levelsHeart failure patientsMode of deathHb levelsHF patientsFailure patientsCardiac deathEjection fractionHemoglobin levelsIncidence of SCDConsecutive acute HF patientsSeattle Proportional Risk ModelDischarge hemoglobin levelsProspective multicentre registryBaseline ejection fractionMean Hb levelNon-cardiovascular causesSeverity of anemiaSCD risk predictionProportional risk modelFailure deathHF management
2020
Prediction of sudden cardiac death in Japanese heart failure patients: international validation of the Seattle Proportional Risk Model.
Fukuoka R, Kohno T, Kohsaka S, Shiraishi Y, Sawano M, Abe T, Nagatomo Y, Goda A, Mizuno A, Fukuda K, Shadman R, Dardas T, Levy W, Yoshikawa T. Prediction of sudden cardiac death in Japanese heart failure patients: international validation of the Seattle Proportional Risk Model. EP Europace 2020, 22: 588-597. PMID: 32155253, DOI: 10.1093/europace/euaa002.Peer-Reviewed Original ResearchConceptsSeattle Proportional Risk ModelSudden cardiac deathHF patientsProportional risk modelCardiac deathHeart failureIncidence of SCDJapanese heart failure patientsAcute HF patientsICD eligibility criteriaReduced ejection fractionHeart failure patientsHosmer-Lemeshow statisticHF registryAcute decompensationCumulative incidenceFailure patientsEjection fractionC-statisticJapanese RegistryJapanese patientsC-indexSCD predictionEligibility criteriaPatients
2018
Validation and Recalibration of Seattle Heart Failure Model in Japanese Acute Heart Failure Patients
Shiraishi Y, Kohsaka S, Nagai T, Goda A, Mizuno A, Nagatomo Y, Sujino Y, Fukuoka R, Sawano M, Kohno T, Fukuda K, Anzai T, Shadman R, Dardas T, Levy W, Yoshikawa T. Validation and Recalibration of Seattle Heart Failure Model in Japanese Acute Heart Failure Patients. Journal Of Cardiac Failure 2018, 25: 561-567. PMID: 30099192, DOI: 10.1016/j.cardfail.2018.07.463.Peer-Reviewed Original ResearchConceptsSeattle Heart Failure ModelHeart failure patientsHF patientsHeart failure modelHFrEF patientsHFpEF patientsEjection fractionFailure patientsAcute heart failure patientsAcute HF patientsConventional clinical variablesJapanese HF patientsReduced ejection fractionPrecise risk stratificationAcute decompensationHeart failureHospital admissionNational CerebralRisk stratificationClinical variablesC-statisticHeart failure databaseModest discriminationPatientsMedical resourcesP5667Predicting sudden cardiac death in Japanese heart failure patients: International validation of the Seattle Proportional Risk Model
Fukuoka R, Kohno T, Kohsaka S, Shiraishi Y, Sawano M, Abe T, Nagatomo Y, Goda A, Mizuno A, Fukuda K, Shadman R, Dardas T, Levy W, Yoshikawa T. P5667Predicting sudden cardiac death in Japanese heart failure patients: International validation of the Seattle Proportional Risk Model. European Heart Journal 2018, 39: ehy566.p5667. DOI: 10.1093/eurheartj/ehy566.p5667.Peer-Reviewed Original Research
2017
PERFORMANCE OF THE MAGGIC HEART FAILURE RISK SCORE IN JAPANESE ACUTE HEART FAILURE PATIENTS: A REPORT FROM THE WEST TOKYO HEART FAILURE REGISTRY
Sawano M, Inohara T, Shiraishi Y, Kohsaka S, Kohno T, Goda A, Mizuno A, Sujino Y, Nagatomo Y, Mahara K, Fukuda K, Yoshikawa T. PERFORMANCE OF THE MAGGIC HEART FAILURE RISK SCORE IN JAPANESE ACUTE HEART FAILURE PATIENTS: A REPORT FROM THE WEST TOKYO HEART FAILURE REGISTRY. Journal Of The American College Of Cardiology 2017, 69: 947. DOI: 10.1016/s0735-1097(17)34336-x.Peer-Reviewed Original Research
2015
Effect of Estimated Plasma Volume Reduction on Renal Function for Acute Heart Failure Differs Between Patients With Preserved and Reduced Ejection Fraction
Takei M, Kohsaka S, Shiraishi Y, Goda A, Izumi Y, Yagawa M, Mizuno A, Sawano M, Inohara T, Kohno T, Fukuda K, Yoshikawa T. Effect of Estimated Plasma Volume Reduction on Renal Function for Acute Heart Failure Differs Between Patients With Preserved and Reduced Ejection Fraction. Circulation Heart Failure 2015, 8: 527-532. PMID: 25737498, DOI: 10.1161/circheartfailure.114.001734.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdministration, IntravenousAgedAged, 80 and overChi-Square DistributionDisease ProgressionDiuresisDiureticsFemaleHeart FailureHumansIdeal Body WeightKidneyLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPlasma VolumeRegistriesRenal Insufficiency, ChronicRetrospective StudiesRisk FactorsStroke VolumeTime FactorsTokyoTreatment OutcomeVentricular Function, LeftConceptsPlasma volume reductionAcute heart failureHeart failureRenal functionEjection fractionBody weightWest Tokyo Heart Failure registryAcute heart failure patientsReduced ejection fraction cohortReduced ejection fraction groupEjection fraction groupHeart Failure RegistryReduced ejection fractionHistory of hypertensionGlomerular filtration rateHeart failure patientsIdeal body weightSubject's body weightVolume reductionHFpEF cohortIntravenous diureticsFailure patientsHemodynamic effectsDiabetes mellitusKidney function
2014
Prognostic Implication of Physical Signs of Congestion in Acute Heart Failure Patients and Its Association with Steady-State Biomarker Levels
Negi S, Sawano M, Kohsaka S, Inohara T, Shiraishi Y, Kohno T, Maekawa Y, Sano M, Yoshikawa T, Fukuda K. Prognostic Implication of Physical Signs of Congestion in Acute Heart Failure Patients and Its Association with Steady-State Biomarker Levels. PLOS ONE 2014, 9: e96325. PMID: 24802880, PMCID: PMC4011709, DOI: 10.1371/journal.pone.0096325.Peer-Reviewed Original ResearchConceptsJugular venous distensionAcute heart failurePulmonary ralesTime of dischargePhysical findingsReadmission ratesAHF patientsAcute heart failure patientsElevated troponin T levelsSingle-center university hospitalConsecutive AHF patientsElevated TnT levelsParoxysmal nocturnal dyspneaNon-ischemic etiologyTroponin T levelsHeart failure patientsNon-ischemic cardiomyopathyLong-term outcomesTime of admissionThird heart soundNocturnal dyspneaMean followPrimary endpointVenous distensionFailure patients