Featured Publications
Performance of the MAGGIC heart failure risk score and its modification with the addition of discharge natriuretic peptides
Sawano M, Shiraishi Y, Kohsaka S, Nagai T, Goda A, Mizuno A, Sujino Y, Nagatomo Y, Kohno T, Anzai T, Fukuda K, Yoshikawa T. Performance of the MAGGIC heart failure risk score and its modification with the addition of discharge natriuretic peptides. ESC Heart Failure 2018, 5: 610-619. PMID: 29520978, PMCID: PMC6073038, DOI: 10.1002/ehf2.12278.Peer-Reviewed Original ResearchConceptsMAGGIC scoreBNP levelsB-type natriuretic peptide levelsAcute Heart Failure registryChronic Heart Failure (MAGGIC) scoreConsecutive acute HF patientsHeart failure patient outcomesHeart Failure Risk ScoreMeta-Analysis Global GroupAcute HF patientsHeart Failure RegistryHeart failure scoreProspective multicentre registryIncremental prognostic valueNatriuretic peptide levelsHeart failure patientsMulticentre registryHF patientsFailure patientsYear mortalityNatriuretic peptidePatient mortalityPrognostic valueMean ageJapanese Registry
2021
Sudden cardiac death after acute decompensation in heart failure patients: implications of discharge haemoglobin levels
Fukuoka R, Kohsaka S, Shiraishi Y, Sawano M, Abe T, Levy W, Nagatomo Y, Nishihata Y, Goda A, Kohno T, Kawamura A, Fukuda K, Yoshikawa T. Sudden cardiac death after acute decompensation in heart failure patients: implications of discharge haemoglobin levels. ESC Heart Failure 2021, 8: 3917-3928. PMID: 34323007, PMCID: PMC8497203, DOI: 10.1002/ehf2.13414.Peer-Reviewed Original ResearchConceptsSudden cardiac deathPump failure deathAcute HF patientsDischarge Hb levelsHeart failure patientsMode of deathHb levelsHF patientsFailure patientsCardiac deathEjection fractionHemoglobin levelsIncidence of SCDConsecutive acute HF patientsSeattle Proportional Risk ModelDischarge hemoglobin levelsProspective multicentre registryBaseline ejection fractionMean Hb levelNon-cardiovascular causesSeverity of anemiaSCD risk predictionProportional risk modelFailure deathHF management
2020
Prediction of sudden cardiac death in Japanese heart failure patients: international validation of the Seattle Proportional Risk Model.
Fukuoka R, Kohno T, Kohsaka S, Shiraishi Y, Sawano M, Abe T, Nagatomo Y, Goda A, Mizuno A, Fukuda K, Shadman R, Dardas T, Levy W, Yoshikawa T. Prediction of sudden cardiac death in Japanese heart failure patients: international validation of the Seattle Proportional Risk Model. EP Europace 2020, 22: 588-597. PMID: 32155253, DOI: 10.1093/europace/euaa002.Peer-Reviewed Original ResearchConceptsSeattle Proportional Risk ModelSudden cardiac deathHF patientsProportional risk modelCardiac deathHeart failureIncidence of SCDJapanese heart failure patientsAcute HF patientsICD eligibility criteriaReduced ejection fractionHeart failure patientsHosmer-Lemeshow statisticHF registryAcute decompensationCumulative incidenceFailure patientsEjection fractionC-statisticJapanese RegistryJapanese patientsC-indexSCD predictionEligibility criteriaPatients
2019
Discrepancy between patient-reported quality of life and the prognostic assessment of Japanese patients hospitalized with acute heart failure
Shoji S, Shiraishi Y, Sawano M, Katsumata Y, Yuasa S, Kohno T, Fukuda K, Spertus J, Kohsaka S. Discrepancy between patient-reported quality of life and the prognostic assessment of Japanese patients hospitalized with acute heart failure. Heart And Vessels 2019, 34: 1464-1470. PMID: 30887105, DOI: 10.1007/s00380-019-01378-1.Peer-Reviewed Original ResearchConceptsClinical risk scorePatient-reported qualityLong-term prognosisHeart failureHHF patientsRisk scoreComposite outcomeAcute settingGWTG-HF risk scoreHospitalized HF patientsAcute heart failureChronic heart failurePrimary therapeutic targetHealth care providersFirst yearCause mortalityHF patientsHF readmissionPatient characteristicsIndependent predictorsAcute phasePrognostic indicatorJapanese patientsPrognostic assessmentCare providers
2018
Validation and Recalibration of Seattle Heart Failure Model in Japanese Acute Heart Failure Patients
Shiraishi Y, Kohsaka S, Nagai T, Goda A, Mizuno A, Nagatomo Y, Sujino Y, Fukuoka R, Sawano M, Kohno T, Fukuda K, Anzai T, Shadman R, Dardas T, Levy W, Yoshikawa T. Validation and Recalibration of Seattle Heart Failure Model in Japanese Acute Heart Failure Patients. Journal Of Cardiac Failure 2018, 25: 561-567. PMID: 30099192, DOI: 10.1016/j.cardfail.2018.07.463.Peer-Reviewed Original ResearchConceptsSeattle Heart Failure ModelHeart failure patientsHF patientsHeart failure modelHFrEF patientsHFpEF patientsEjection fractionFailure patientsAcute heart failure patientsAcute HF patientsConventional clinical variablesJapanese HF patientsReduced ejection fractionPrecise risk stratificationAcute decompensationHeart failureHospital admissionNational CerebralRisk stratificationClinical variablesC-statisticHeart failure databaseModest discriminationPatientsMedical resources
2017
Current use of guideline-based medical therapy in elderly patients admitted with acute heart failure with reduced ejection fraction and its impact on event-free survival
Akita K, Kohno T, Kohsaka S, Shiraishi Y, Nagatomo Y, Izumi Y, Goda A, Mizuno A, Sawano M, Inohara T, Fukuda K, Yoshikawa T, Investigators W. Current use of guideline-based medical therapy in elderly patients admitted with acute heart failure with reduced ejection fraction and its impact on event-free survival. International Journal Of Cardiology 2017, 235: 162-168. PMID: 28259550, DOI: 10.1016/j.ijcard.2017.02.070.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAge FactorsAgedAged, 80 and overAngiotensin-Converting Enzyme InhibitorsFemaleHeart FailureHumansJapanMaleMedication Therapy ManagementMiddle AgedNeeds AssessmentOutcome and Process Assessment, Health CarePatient DischargePatient ReadmissionPractice Guidelines as TopicStroke VolumeVentricular Dysfunction, LeftConceptsGuideline-based medical therapyAcute heart failureReduced ejection fractionElderly patientsHeart failureEjection fractionHF readmissionMedical therapyWest Tokyo Heart Failure registryConsecutive acute HF patientsYounger groupAcute HF patientsElderly HFrEF patientsHeart Failure RegistryEvent-free survivalMulti-center registryIdeal therapeutic approachHF rehospitalizationHFrEF patientsHF patientsCurrent useCardiac deathComposite endpointPrescription ratesPoor outcome