2021
A Novel Risk Stratification System for Ischemic Stroke in Japanese Patients With Non-Valvular Atrial Fibrillation
Okumura K, Tomita H, Nakai M, Kodani E, Akao M, Suzuki S, Hayashi K, Sawano M, Goya M, Yamashita T, Fukuda K, Ogawa H, Tsuda T, Isobe M, Toyoda K, Miyamoto Y, Miyata H, Okamura T, Sasahara Y, Group F. A Novel Risk Stratification System for Ischemic Stroke in Japanese Patients With Non-Valvular Atrial Fibrillation. Circulation Journal 2021, 85: 1254-1262. PMID: 33762526, DOI: 10.1253/circj.cj-20-1075.Peer-Reviewed Original ResearchConceptsJapanese NVAF patientsIndependent risk factorIschemic strokeNVAF patientsRisk factorsAF RegistryHazard ratioC-statisticJapanese non-valvular atrial fibrillation (NVAF) patientsNon-valvular atrial fibrillation patientsCox hazard proportional analysisNovel risk stratification systemNon-valvular atrial fibrillationLower body mass indexFushimi AF RegistryIschemic stroke eventsJ-RHYTHM RegistryAtrial fibrillation patientsOral anticoagulant treatmentBody mass indexSignificant risk factorsRisk stratification systemType of AFVASc scoreAnticoagulant treatment
2020
Prediction of sudden cardiac death in Japanese heart failure patients: international validation of the Seattle Proportional Risk Model.
Fukuoka R, Kohno T, Kohsaka S, Shiraishi Y, Sawano M, Abe T, Nagatomo Y, Goda A, Mizuno A, Fukuda K, Shadman R, Dardas T, Levy W, Yoshikawa T. Prediction of sudden cardiac death in Japanese heart failure patients: international validation of the Seattle Proportional Risk Model. EP Europace 2020, 22: 588-597. PMID: 32155253, DOI: 10.1093/europace/euaa002.Peer-Reviewed Original ResearchConceptsSeattle Proportional Risk ModelSudden cardiac deathHF patientsProportional risk modelCardiac deathHeart failureIncidence of SCDJapanese heart failure patientsAcute HF patientsICD eligibility criteriaReduced ejection fractionHeart failure patientsHosmer-Lemeshow statisticHF registryAcute decompensationCumulative incidenceFailure patientsEjection fractionC-statisticJapanese RegistryJapanese patientsC-indexSCD predictionEligibility criteriaPatients
2018
Validation and Recalibration of Seattle Heart Failure Model in Japanese Acute Heart Failure Patients
Shiraishi Y, Kohsaka S, Nagai T, Goda A, Mizuno A, Nagatomo Y, Sujino Y, Fukuoka R, Sawano M, Kohno T, Fukuda K, Anzai T, Shadman R, Dardas T, Levy W, Yoshikawa T. Validation and Recalibration of Seattle Heart Failure Model in Japanese Acute Heart Failure Patients. Journal Of Cardiac Failure 2018, 25: 561-567. PMID: 30099192, DOI: 10.1016/j.cardfail.2018.07.463.Peer-Reviewed Original ResearchConceptsSeattle Heart Failure ModelHeart failure patientsHF patientsHeart failure modelHFrEF patientsHFpEF patientsEjection fractionFailure patientsAcute heart failure patientsAcute HF patientsConventional clinical variablesJapanese HF patientsReduced ejection fractionPrecise risk stratificationAcute decompensationHeart failureHospital admissionNational CerebralRisk stratificationClinical variablesC-statisticHeart failure databaseModest discriminationPatientsMedical resources
2016
Validation of the european SCORE risk chart in the healthy middle-aged Japanese
Sawano M, Kohsaka S, Okamura T, Inohara T, Sugiyama D, Watanabe M, Nakamura Y, Higashiyama A, Kadota A, Okud N, Murakami Y, Ohkubo T, Fujiyoshi A, Miura K, Okayama A, Ueshima H, Group F. Validation of the european SCORE risk chart in the healthy middle-aged Japanese. Atherosclerosis 2016, 252: 116-121. PMID: 27521900, DOI: 10.1016/j.atherosclerosis.2016.07.926.Peer-Reviewed Original ResearchConceptsCardiovascular death riskMiddle-aged JapaneseC-statisticDeath riskScore modelEuropean SCORE risk chartsOverall populationHarrel's c-statisticsSCORE risk chartsJapanese general populationHigh-risk populationGeneral Japanese populationCV deathRisk chartsGeneral populationEuropean SocietyJapanese populationDifferent ethnicitiesWomenPoor calibrationReasonable discriminationRiskMenPopulationTen years
2015
Validation of the Get With The Guideline–Heart Failure risk score in Japanese patients and the potential improvement of its discrimination ability by the inclusion of B-type natriuretic peptide level
Shiraishi Y, Kohsaka S, Abe T, Mizuno A, Goda A, Izumi Y, Yagawa M, Akita K, Sawano M, Inohara T, Takei M, Kohno T, Higuchi S, Yamazoe M, Mahara K, Fukuda K, Yoshikawa T, Investigators W. Validation of the Get With The Guideline–Heart Failure risk score in Japanese patients and the potential improvement of its discrimination ability by the inclusion of B-type natriuretic peptide level. American Heart Journal 2015, 171: 33-39. PMID: 26699598, DOI: 10.1016/j.ahj.2015.10.008.Peer-Reviewed Original ResearchConceptsB-type natriuretic peptide levelsGWTG-HF risk scoreAcute heart failureNatriuretic peptide levelsHospital mortalityRisk scorePeptide levelsAHF patientsC-statisticGuidelines-Heart Failure (GWTG-HF) risk scoreWest Tokyo Heart Failure registryChronic obstructive pulmonary diseaseBlood urea nitrogen levelsGWTG-HF scoreHeart Failure RegistryMulticenter cohort registryRisk score performanceObstructive pulmonary diseaseSystolic blood pressureUrea nitrogen levelsHosmer-Lemeshow statisticFuture risk modelsCohort registryBlood pressureHeart failure