2024
Sometimes, the size matters: Wing geometric morphometrics as a tool to assess domiciliation by Triatoma sordida (Stäl 1859)
Ribeiro-Jr G, Reis J, Vaccarezza F, Silva A, Lanza F, Miranda D, Gurgel-Gonçalves R, Reis M. Sometimes, the size matters: Wing geometric morphometrics as a tool to assess domiciliation by Triatoma sordida (Stäl 1859). Revista Da Sociedade Brasileira De Medicina Tropical 2024, 57: e00709-2024. PMID: 39140583, PMCID: PMC11315410, DOI: 10.1590/0037-8682-0516-2023.Peer-Reviewed Original ResearchConceptsWing geometric morphometricsGeometric morphometric analysisPeridomestic populationsTriatoma sordidaWing geometric morphometryGeometric morphometryGeometric morphometricsHousing populationSouth AmericaT. sordidaMorphometric analysisHemelytraPublic health concernDomiciliationMorphometricsPopulation
2023
Dynamics of chikungunya virus transmission in the first year after its introduction in Brazil: A cohort study in an urban community
Anjos R, Portilho M, Jacob-Nascimento L, Carvalho C, Moreira P, Sacramento G, Nery N, de Oliveira D, Cruz J, Cardoso C, Argibay H, Plante K, Plante J, Weaver S, Kitron U, Reis M, Ko A, Costa F, Ribeiro G. Dynamics of chikungunya virus transmission in the first year after its introduction in Brazil: A cohort study in an urban community. PLOS Neglected Tropical Diseases 2023, 17: e0011863. PMID: 38150470, PMCID: PMC10775974, DOI: 10.1371/journal.pntd.0011863.Peer-Reviewed Original ResearchMalaria and COVID-19 coinfection in a non-malaria-endemic area in Brazil
Rocha V, Brasil L, Gomes E, Khouri R, Ferreira G, Vasconcelos B, Gouveia M, Santos T, Reis M, Lacerda M. Malaria and COVID-19 coinfection in a non-malaria-endemic area in Brazil. Revista Da Sociedade Brasileira De Medicina Tropical 2023, 56: e0598-2022. PMID: 37222351, PMCID: PMC10204151, DOI: 10.1590/0037-8682-0598-2022.Peer-Reviewed Original ResearchConceptsCOVID-19 coinfectionSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Respiratory syndrome coronavirus 2Severe vivax malariaIntensive care unitSyndrome coronavirus 2Coronavirus disease 2019Transcription-quantitative PCR resultsSevere malariaCare unitCoronavirus 2Vivax malariaDifferential diagnosisDisease 2019Febrile diseaseEndemic areasPlasmodium vivaxEndemic regionsCoinfectionRapid testMalariaPCR resultsQuantitative PCRHypotension
2022
Structural factors associated with SARS-CoV-2 infection risk in an urban slum setting in Salvador, Brazil: A cross-sectional survey
Fofana MO, Nery N, Ticona J, de Andrade Belitardo EMM, Victoriano R, Anjos RO, Portilho MM, de Santana MC, dos Santos LL, de Oliveira D, Cruz JS, Muenker MC, Khouri R, Wunder EA, Hitchings MDT, Johnson O, Reis MG, Ribeiro GS, Cummings DAT, Costa F, Ko AI. Structural factors associated with SARS-CoV-2 infection risk in an urban slum setting in Salvador, Brazil: A cross-sectional survey. PLOS Medicine 2022, 19: e1004093. PMID: 36074784, PMCID: PMC9499230, DOI: 10.1371/journal.pmed.1004093.Peer-Reviewed Original ResearchConceptsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionAcute respiratory syndrome coronavirus 2 infectionSARS-CoV-2 infection riskUrban slumsSyndrome coronavirus 2 infectionSARS-CoV-2 seroprevalenceSARS-CoV-2 incidenceCoronavirus 2 infectionCross-sectional serosurveyMain outcome measuresUrban slum populationPresence of IgGSARS-CoV-2 spike proteinUrban slum communityCross-sectional surveyUrban slum residentsCumulative incidenceMedian ageRisk factorsOutcome measuresStudy populationHigh seroprevalenceMedian dailyPandemic waveGender distributionUnequal burden of Zika-associated microcephaly among populations with public and private healthcare in Salvador, Brazil
Aromolaran A, Araujo K, Ladines-Lim JB, Nery N, do Rosário MS, Rastely VN, Archanjo G, Daltro D, da Silveira Carvalho G, Pimentel K, de Almeida JRM, de Siqueira IC, Ribeiro HC, Oliveira-Filho J, de Oliveira D, Henriques DF, Rodrigues SG, da Costa Vasconcelos P, de Almeida ARP, Sacramento GA, Cruz JS, Sarno M, de Paula Freitas B, Mattos A, Khouri R, Reis MG, Ko AI, Costa F. Unequal burden of Zika-associated microcephaly among populations with public and private healthcare in Salvador, Brazil. International Journal Of Infectious Diseases 2022, 120: 201-204. PMID: 35470025, PMCID: PMC9119857, DOI: 10.1016/j.ijid.2022.04.030.Peer-Reviewed Original ResearchConceptsZIKV exposurePregnant womenSocioeconomic statusRelative disease burdenCongenital Zika syndromeZika virus epidemicLow socioeconomic statusZika syndromeClinical presentationDisease burdenSimilar prevalenceSerologic dataDifferent socioeconomic statusS HospitalHospitalLarge hospitalsMicrocephalyStudy centersVirus epidemicWomenPositive associationInfantsUnequal burdenHigh rateExposure rateCOVID-19 vaccine hesitancy and associated factors according to sex: A population-based survey in Salvador, Brazil
Nery N, Ticona J, Cardoso C, Prates A, Vieira H, de Almeida A, da Silva Souza M, dos Reis O, Pellizzaro M, Portilho M, da Anunciação R, Victoriano R, dos Anjos R, Argibay H, Lima D, Mesquita I, Conceição W, Santana P, Oliveira E, Santana P, Brodskyn C, Fraga D, da Silva Solcà M, Reis M, Costa F, Ribeiro G. COVID-19 vaccine hesitancy and associated factors according to sex: A population-based survey in Salvador, Brazil. PLOS ONE 2022, 17: e0262649. PMID: 35061811, PMCID: PMC8782400, DOI: 10.1371/journal.pone.0262649.Peer-Reviewed Original ResearchConceptsCOVID-19 vaccine hesitancyVaccine hesitancyCOVID-19 vaccineCOVID-19 riskCOVID-19 vaccine acceptanceInfluenza vaccination historyPopulation-based surveyCoronavirus disease 2019Less vaccine hesitancyHigher educational levelInfluenza vaccinationVaccination historyMultivariable analysisPrevious diagnosisVaccine acceptanceAssociated FactorsVaccine campaignDisease 2019VaccineComorbiditiesHesitancyCOVID-19VaccinationEducational levelWomen
2021
Acute-Phase Levels of CXCL8 as Risk Factor for Chronic Arthralgia Following Chikungunya Virus Infection
Jacob-Nascimento L, Carvalho C, Silva M, Kikuti M, Anjos R, Fradico J, Campi-Azevedo A, Tauro L, Campos G, dos Santos Moreira P, Portilho M, Martins-Filho O, Ribeiro G, Reis M. Acute-Phase Levels of CXCL8 as Risk Factor for Chronic Arthralgia Following Chikungunya Virus Infection. Frontiers In Immunology 2021, 12: 744183. PMID: 34659240, PMCID: PMC8517435, DOI: 10.3389/fimmu.2021.744183.Peer-Reviewed Original ResearchConceptsChikungunya virus infectionCHIKV infectionHealthy controlsIL-12IL-1βVirus infectionFlow cytometric bead arrayAcute phase immune responseAcute CHIKV infectionAnti-CHIKV IgMAcute-phase samplesCytometric bead arrayAcute febrile diseaseAcute-phase levelsCHIKV patientsSerum chemokinesCXCL10 levelsPain persistenceIL-10Cytokine kineticsMultivariable analysisCXCL8 levelsIL-6Female sexIL-2Diagnostic Accuracy of Serum Hyaluronan for Detecting HCV Infection and Liver Fibrosis in Asymptomatic Blood Donors
Rodart I, Pares M, Mendes A, Accardo C, Martins J, Silva C, Carvalho F, Barreto J, Reis M, Tersariol I, Nader H. Diagnostic Accuracy of Serum Hyaluronan for Detecting HCV Infection and Liver Fibrosis in Asymptomatic Blood Donors. Molecules 2021, 26: 3892. PMID: 34202190, PMCID: PMC8270308, DOI: 10.3390/molecules26133892.Peer-Reviewed Original ResearchConceptsHepatitis C virusAsymptomatic blood donorsLiver fibrosisBlood donorsSerum hyaluronanHCV infectionSerum levelsGGT serum levelsHA serum levelsHCV RNA detectionHCV viral loadProgressive liver diseaseAdvanced liver fibrosisHigher ALT levelsSignificant liver fibrosisNormal ALTHCV viremiaALT levelsAntiviral treatmentAsymptomatic personsBiopsy confirmationHCV samplesLiver biomarkersLiver diseaseViral loadAngiostrongylus cantonensis in urban populations of terrestrial gastropods and rats in an impoverished region of Brazil.
Souza F, Aguiar Santos M, Almeida Alves D, Cecília Vieira de Melo L, Jessé Gonçalves da Mota D, Cristina Pertile A, Gava R, Luiz Silva Pinto P, Eyre M, Graco Zeppelini C, Reis M, Ko A, Begon M, Bahiense T, Costa F, Carvalho-Pereira T. Angiostrongylus cantonensis in urban populations of terrestrial gastropods and rats in an impoverished region of Brazil. Parasitology 2021, 148: 994-1002. PMID: 33843507, PMCID: PMC11010192, DOI: 10.1017/s0031182021000597.Peer-Reviewed Original ResearchRisk of chronic arthralgia and impact of pain on daily activities in a cohort of patients with chikungunya virus infection from Brazil
Silva M, Kikuti M, Anjos R, Portilho M, Santos V, Gonçalves T, Tauro L, Moreira P, Jacob-Nascimento L, Santana P, Campos G, Siqueira A, Kitron U, Reis M, Ribeiro G. Risk of chronic arthralgia and impact of pain on daily activities in a cohort of patients with chikungunya virus infection from Brazil. International Journal Of Infectious Diseases 2021, 105: 608-616. PMID: 33684559, DOI: 10.1016/j.ijid.2021.03.003.Peer-Reviewed Original ResearchConceptsChronic arthralgiaChikungunya virus infectionRisk factorsVirus infectionDaily activitiesAcute febrile illnessIndependent risk factorPersistence of painCohort of patientsImpact of painProgression of diseaseTranscriptase-polymerase chain reactionPersistent arthralgiaFebrile illnessSubstantial disabilityViral loadFemale sexPolymerase chain reactionIgM enzymeArthralgiaSurveillance studyChikungunya virusDengue virusPatientsImmunosorbent assay
2020
Outbreak of Stenotrophomonas maltophilia and Burkholderia cepacia Bloodstream Infections at a Hemodialysis Center.
Diniz Rocha V, Cavalcanti T, Azevedo J, Leal H, Oliveira Silva G, Xavier Malheiros A, Ataide L, Lima Filho J, Pinto Almeida A, de Andrade Khouri N, Reis M, Neves Reis J. Outbreak of Stenotrophomonas maltophilia and Burkholderia cepacia Bloodstream Infections at a Hemodialysis Center. American Journal Of Tropical Medicine And Hygiene 2020, 104: 848-853. PMID: 33319730, PMCID: PMC7941797, DOI: 10.4269/ajtmh.20-1035.Peer-Reviewed Original ResearchClinical and epidemiological features of pertussis in Salvador, Brazil, 2011–2016
Araújo L, Nunes A, Ferreira V, Cardoso C, Feitosa C, Reis M, Campos L. Clinical and epidemiological features of pertussis in Salvador, Brazil, 2011–2016. PLOS ONE 2020, 15: e0238932. PMID: 32915869, PMCID: PMC7485779, DOI: 10.1371/journal.pone.0238932.Peer-Reviewed Original ResearchConceptsPertussis casesChi-square testUnvaccinated individualsClinical criteriaExact testComplete vaccination scheduleSevere respiratory infectionsPrevention of pertussisPearson's chi-square testFisher's exact testAge group 2Paroxysmal coughRespiratory infectionsVaccination scheduleRetrospective studyEpidemiological featuresLaboratory criteriaVaccination strategiesClinical dataEpidemiological aspectsGroup 2More symptomsCase confirmationNumber of casesBivariate analysisMeningococcal carriage in young adults six years after meningococcal C conjugate (MCC) vaccine catch-up campaign in Salvador, Brazil
Ferreira V, Ferreira Í, Chang H, Nunes A, Topaz N, Pimentel E, Moura A, Ribeiro G, Feitosa C, Reis M, Wang X, Campos L. Meningococcal carriage in young adults six years after meningococcal C conjugate (MCC) vaccine catch-up campaign in Salvador, Brazil. Vaccine 2020, 38: 2995-3002. PMID: 32115294, DOI: 10.1016/j.vaccine.2020.02.050.Peer-Reviewed Original ResearchConceptsMeningococcal carriageCarriage prevalenceRT-PCRN. meningitidisYoung adultsMeningococcal carriage studyMeningococcal serogroup CCross-sectional studyMeningococcal carriage prevalenceAppropriate vaccination strategiesStandard microbiology methodsSix yearsMeningococcal carriage isolatesNG isolatesMale sexSerogroup CHerd protectionVaccination strategiesCarriage isolatesCarriage studiesOropharyngeal swabsReal-time PCRNull genotypeContinuous vaccinationNeisseria meningitidisInfluence of Rainfall on Leptospira Infection and Disease in a Tropical Urban Setting, Brazil - Volume 26, Number 2—February 2020 - Emerging Infectious Diseases journal - CDC
Hacker KP, Sacramento GA, Cruz JS, de Oliveira D, Nery N, Lindow JC, Carvalho M, Hagan J, Diggle PJ, Begon M, Reis MG, Wunder EA, Ko AI, Costa F. Influence of Rainfall on Leptospira Infection and Disease in a Tropical Urban Setting, Brazil - Volume 26, Number 2—February 2020 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2020, 26: 311-314. PMID: 31961288, PMCID: PMC6986844, DOI: 10.3201/eid2602.190102.Peer-Reviewed Original Research
2019
Evaluation of two commercially available chikungunya virus IgM enzyme-linked immunoassays (ELISA) in a setting of concomitant transmission of chikungunya, dengue and Zika viruses
Kikuti M, Tauro L, Moreira P, Nascimento L, Portilho M, Soares G, Weaver S, Reis M, Kitron U, Ribeiro G. Evaluation of two commercially available chikungunya virus IgM enzyme-linked immunoassays (ELISA) in a setting of concomitant transmission of chikungunya, dengue and Zika viruses. International Journal Of Infectious Diseases 2019, 91: 38-43. PMID: 31704226, DOI: 10.1016/j.ijid.2019.11.001.Peer-Reviewed Original ResearchConceptsConvalescent samplesIgM enzymeRT-PCRZika virus transmissionNegative patientsCHIKV infectionAcute samplesZIKV casesConvalescent seraSurveillance studyCHIKV transmissionZika virusCHIKV casesDiagnostic performanceLow specificityVirus transmissionEquivocal resultsTest sensitivitySerumELISA specificityPatientsHigh rateDengueConcomitant transmissionMore equivocal resultsBloodstream infections caused by multidrug-resistant gram-negative bacteria: epidemiological, clinical and microbiological features
Leal H, Azevedo J, Silva G, Amorim A, de Roma L, Arraes A, Gouveia E, Reis M, Mendes A, de Oliveira Silva M, Barberino M, Martins I, Reis J. Bloodstream infections caused by multidrug-resistant gram-negative bacteria: epidemiological, clinical and microbiological features. BMC Infectious Diseases 2019, 19: 609. PMID: 31296179, PMCID: PMC6624930, DOI: 10.1186/s12879-019-4265-z.Peer-Reviewed Original ResearchConceptsK. pneumoniaePrevious antimicrobial useLaboratory-based surveillanceAntimicrobial susceptibility testingMDR bacteremiaMDR-GNBDrug-resistant pathogensNegative bacteremiaLiver diseaseBloodstream infectionsHigh morbidityMale sexRisk factorsEpidemiological aspectsNegative bacilliHealthcare professionalsMicrobiological featuresSusceptibility testingBacteremiaInfectionAntimicrobial useCausative agentAntibiotic resistanceIntervention measuresResistance determinantsAccuracy of the SD BIOLINE Dengue Duo for rapid point-of-care diagnosis of dengue
Kikuti M, Cruz J, Rodrigues M, Tavares A, Paploski I, Silva M, Santana P, Tauro L, Silva G, Campos G, Araújo J, Kitron U, Reis M, Ribeiro G. Accuracy of the SD BIOLINE Dengue Duo for rapid point-of-care diagnosis of dengue. PLOS ONE 2019, 14: e0213301. PMID: 30840708, PMCID: PMC6402663, DOI: 10.1371/journal.pone.0213301.Peer-Reviewed Original ResearchConceptsRapid diagnosis testsNon-dengue febrile patientsFebrile patientsHealthy controlsBlood donorsLaboratory-confirmed dengue casesSD BIOLINE Dengue DuoSecondary DENV infectionDengue virus antigenAcute-phase seraDengue diagnostic testsRepresentative serum samplesDengue-endemic regionsDengue-endemic areasSample of casesDENV antibodiesDENV infectionNS1 ELISAPrimary infectionDengue diagnosisMedical treatment decisionsTreatment decisionsVirus antigenRDT accuracyRDT sensitivityA localized outbreak of Chikungunya virus in Salvador, Bahia, Brazil
Tauro L, Cardoso C, Souza R, Nascimento L, dos Santos D, Campos G, Sardi S, dos Reis O, Reis M, Kitron U, Ribeiro G. A localized outbreak of Chikungunya virus in Salvador, Bahia, Brazil. Memórias Do Instituto Oswaldo Cruz 2019, 114: e180597. PMID: 30843962, PMCID: PMC6396974, DOI: 10.1590/0074-02760180597.Peer-Reviewed Original Research
2016
Genetic profiles and antimicrobial resistance of Streptococcus pneumoniae non-PCV10 serotype isolates recovered from meningitis cases in Salvador, Brazil
Azevedo J, Dos Anjos ES, Cordeiro S, Dos Santos M, Escobar E, Lobo P, Carvalho MD, Reis M, Reis J, Campos L. Genetic profiles and antimicrobial resistance of Streptococcus pneumoniae non-PCV10 serotype isolates recovered from meningitis cases in Salvador, Brazil. Journal Of Medical Microbiology 2016, 65: 1164-1170. PMID: 27599851, DOI: 10.1099/jmm.0.000346.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBrazilChildChild, PreschoolDrug Resistance, BacterialElectrophoresis, Gel, Pulsed-FieldFemaleGenetic VariationGenotypeHospitalsHumansInfantMaleMeningitis, PneumococcalMicrobial Sensitivity TestsMiddle AgedMolecular EpidemiologyMultilocus Sequence TypingMultiplex Polymerase Chain ReactionPneumococcal VaccinesSerogroupSerotypingStreptococcus pneumoniaeYoung AdultConceptsPost-vaccine periodMulti-locus sequence typing resultsIntroduction of PCV10Non-vaccine serotypesCases of meningitisPneumococcal conjugate vaccineBenefits of vaccinationChildhood vaccination programsAntimicrobial susceptibility testingMulti-locus sequence typingPCV10 introductionPneumococcal meningitisConjugate vaccineReference hospitalSerotype 19AMeningitis casesSerotype 12FVaccination programMore antibioticsSerotype isolatesQuellung reactionE-testStreptococcus pneumoniaeMeningitisSusceptibility testingLeptospira in breast tissue and milk of urban Norway rats (Rattus norvegicus)
DE OLIVEIRA D, FIGUEIRA CP, ZHAN L, PERTILE AC, PEDRA GG, GUSMÃO IM, WUNDER EA, RODRIGUES G, RAMOS EA, KO AI, CHILDS JE, REIS MG, COSTA F. Leptospira in breast tissue and milk of urban Norway rats (Rattus norvegicus). Epidemiology And Infection 2016, 144: 2420-2429. PMID: 27019024, PMCID: PMC5437553, DOI: 10.1017/s0950268816000637.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionBreast tissuePresence of leptospiresNorway ratsMajor public health concernMilk-borne transmissionMajor pathological changesReal-time polymerase chain reactionPublic health concernQuantitative real-time polymerase chain reactionPathogenic Leptospira sppBreast tissue samplesChronic carriagePathological changesLactating ratsRatsHealth concernImmunofluorescence assaysLeptospira sppGenus LeptospiraTissue samplesUrban slumsChain reactionLeptospiresLeptospira