Expression Levels of CD11b, CD18, CD32, CD62L (L-Selectin) and CD62P (P-Selectin) and Its Role in Sickle Cell Anemia Inflammatory State
Cerqueira B, Boas W, Seixas M, Damasceno E, Souza C, Reis M, Goncalves M. Expression Levels of CD11b, CD18, CD32, CD62L (L-Selectin) and CD62P (P-Selectin) and Its Role in Sickle Cell Anemia Inflammatory State. Blood 2008, 112: 2504. DOI: 10.1182/blood.v112.11.2504.2504.Peer-Reviewed Original ResearchVaso-occlusive eventsInflammatory stateVascular occlusionSCA patientsRed blood cellsLeukocyte activationHemolytic stateExpression levelsSickle cell complicationsExpression of CD62LHigher CRP levelsSoluble adhesion moleculesChronic inflammatory stateVenous blood samplesNaïve T lymphocytesHigh endothelial venulesFetal hemoglobinActivation stateCD62L expression levelsCell surface antigensLeukocyte cell surface antigensVascular complicationsCD62L expressionCRP levelsEndothelial dysfunction