2011
Lymphocyte Surface Molecule Expression on Basal State and After Challenge: Association of Clinical Profile, Inflammation, Hematological and Biochemical Markers in Sickle Cell Anemia Patients
Cerqueira B, Vilas-Boas W, Zanette A, Clarencio J, Salvino M, Cezar R, Andrade D, Reis M, Goncalves M. Lymphocyte Surface Molecule Expression on Basal State and After Challenge: Association of Clinical Profile, Inflammation, Hematological and Biochemical Markers in Sickle Cell Anemia Patients. Blood 2011, 118: 2146. DOI: 10.1182/blood.v118.21.2146.2146.Peer-Reviewed Original ResearchSickle cell anemia patientsSoluble adhesion moleculesSickle cell anemiaSurface molecule expressionSCA patientsControl groupAnemia patientsAdhesion moleculesLymphocyte expressionLPS challengeMedical historyCD18 expressionMolecule expressionSoluble vascular adhesion moleculeBasal statePro-inflammatory interactionsEffector immune responsesVaso-occlusive episodesExpression of CD62LMarkers of inflammationChronic inflammatory stateTNF-alpha valuesVascular adhesion moleculesComplete medical historyExpression of CD11b
2008
Expression Levels of CD11b, CD18, CD32, CD62L (L-Selectin) and CD62P (P-Selectin) and Its Role in Sickle Cell Anemia Inflammatory State
Cerqueira B, Boas W, Seixas M, Damasceno E, Souza C, Reis M, Goncalves M. Expression Levels of CD11b, CD18, CD32, CD62L (L-Selectin) and CD62P (P-Selectin) and Its Role in Sickle Cell Anemia Inflammatory State. Blood 2008, 112: 2504. DOI: 10.1182/blood.v112.11.2504.2504.Peer-Reviewed Original ResearchVaso-occlusive eventsInflammatory stateVascular occlusionSCA patientsRed blood cellsLeukocyte activationHemolytic stateExpression levelsSickle cell complicationsExpression of CD62LHigher CRP levelsSoluble adhesion moleculesChronic inflammatory stateVenous blood samplesNaïve T lymphocytesHigh endothelial venulesFetal hemoglobinActivation stateCD62L expression levelsCell surface antigensLeukocyte cell surface antigensVascular complicationsCD62L expressionCRP levelsEndothelial dysfunction