2010
Iinsulin Levels and Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) May Explain a Possible Important Role of the Pancreas In Sickle Cell Disease Patients Outcome
Seixas M, Lopes V, Cezar R, Carvalho G, Rocha L, Lyra I, Reis M, Goncalves M. Iinsulin Levels and Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) May Explain a Possible Important Role of the Pancreas In Sickle Cell Disease Patients Outcome. Blood 2010, 116: 4811. DOI: 10.1182/blood.v116.21.4811.4811.Peer-Reviewed Original ResearchSickle cell diseaseC-reactive proteinInsulin levelsBlood cell countSCD patientsAspartate aminotransferaseHOMA-IRWBC countLactate dehydrogenaseHemoglobin concentrationCell countSeverity of SCDChronic sub-clinical inflammationWhite blood cell countSub-clinical inflammationHigher insulin levelsRed blood cell countCross-sectional studyLower insulin levelsHigher ferritin concentrationsHigher haptoglobin concentrationsImportant biomarkerInflammatory markersPain episodesChronic inflammation
2000
Hepatitis C virus genotypes in a northeastern area of Brazil.
Silva L, Paraná R, Souza S, Berby F, Kay A, Trepó C, Santana N, Cotrim H, Lyra L, Reis M. Hepatitis C virus genotypes in a northeastern area of Brazil. American Journal Of Tropical Medicine And Hygiene 2000, 62: 257-60. PMID: 10813481, DOI: 10.4269/ajtmh.2000.62.257.Peer-Reviewed Original ResearchConceptsHepatitis C virusReverse transcription-polymerase chain reactionC virusGenotyping of HCVTranscription-polymerase chain reactionSeropositive serum samplesGenotype-specific primersWarrants further investigationGenotype 3Subtype 1aAlanine aminotransferaseGenotype distributionAspartate aminotransferaseSerum samplesMixed genotypesChain reactionViral RNACity of SalvadorFurther investigationAminotransferaseVirusBrazilian samplePatientsHigh frequencyGenotypes