2023
The serotype-specific prevalence of pneumococci in hospitalized pneumonia patients with COPD: a prospective, multi-center, cohort study
Kim J, Jung J, Kang M, Kim D, Choi H, Cho Y, Jang S, Lee C, Oh Y, Park J. The serotype-specific prevalence of pneumococci in hospitalized pneumonia patients with COPD: a prospective, multi-center, cohort study. The Korean Journal Of Internal Medicine 2023, 38: 714-724. PMID: 37586811, PMCID: PMC10493435, DOI: 10.3904/kjim.2023.152.Peer-Reviewed Original ResearchConceptsCommunity-acquired pneumoniaSerotype-specific prevalencePneumococcal pneumoniaCohort studyS. pneumoniaeChronic obstructive pulmonary disease patientsPneumococcal polysaccharide vaccine 23Obstructive pulmonary disease patientsPCV-13 vaccinationUrine antigen detectionPulmonary disease patientsCommon pneumococcal serotypesPost-vaccination eraPneumococcal vaccinationSerotype 22FCOPD patientsInfluenza vaccinationPCV-13Clinical characteristicsVaccination statusOverall incidencePneumonia patientsPPV-23Pneumococcal serotypesVaccination rates
2020
Retrograde signaling by a mtDNA-encoded non-coding RNA preserves mitochondrial bioenergetics
Blumental-Perry A, Jobava R, Bederman I, Degar A, Kenche H, Guan B, Pandit K, Perry N, Molyneaux N, Wu J, Prendergas E, Ye Z, Zhang J, Nelson C, Ahangari F, Krokowski D, Guttentag S, Linden P, Townsend D, Miron A, Kang M, Kaminski N, Perry Y, Hatzoglou M. Retrograde signaling by a mtDNA-encoded non-coding RNA preserves mitochondrial bioenergetics. Communications Biology 2020, 3: 626. PMID: 33127975, PMCID: PMC7603330, DOI: 10.1038/s42003-020-01322-4.Peer-Reviewed Original ResearchConceptsMitochondrial genomeNuclear-encoded genesCell type-specific mannerNon-coding RNASteady-state transcriptionMitochondrial energy metabolismControl regionPositive regulationMitochondrial bioenergeticsMitochondria stressMitochondrial functionSpecific mannerAlveolar epithelial type II cellsEnergy metabolismType II cellsEpithelial type II cellsGenomePhysiological stressRNAII cellsCellsMouse lungTranscriptionGenesMitochondria
2003
Lung Matrix Metalloproteinase-9 Correlates with Cigarette Smoking and Obstruction of Airflow
Kang M, Oh Y, Lee J, Kim D, Park M, Lee M, Hyun I, Han S, Shim Y, Jung K. Lung Matrix Metalloproteinase-9 Correlates with Cigarette Smoking and Obstruction of Airflow. Journal Of Korean Medical Science 2003, 18: 821-827. PMID: 14676438, PMCID: PMC3055149, DOI: 10.3346/jkms.2003.18.6.821.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseMMP-9 concentrationsCigarette smokingMMP-9Matrix metalloproteinasesTIMP-1Lung parenchymaCharacteristics of COPDPathogenesis of COPDObstructive pulmonary diseaseMatrix metalloproteinase-9 correlatesImportant risk factorMMP-9 expressionObstruction of airflowHuman lung parenchymaFEV1 valuesPulmonary diseaseRisk factorsMMP expressionSmokingTissue inhibitorObstructionGelatinolytic bandsEnzyme immunoassayZymographic analysis