2021
Relating neural processing of reward and loss prospect to risky decision-making in individuals with and without gambling disorder
Balodis I, Linnet J, Arshad F, Worhunsky P, Stevens M, Pearlson G, Potenza M. Relating neural processing of reward and loss prospect to risky decision-making in individuals with and without gambling disorder. 2021, 97-113. DOI: 10.4324/9781003140450-7.ChaptersMonetary incentive delay taskIowa Gambling TaskIncentive delay taskGambling disorderAnticipatory processingIGT scoresIGT performanceDelay taskIowa Gambling Task performanceProspect of rewardDecision-making impairmentsGambling Task performanceVentromedial prefrontal cortexDecision-making taskWhole-brain correlationFronto-striatal activityHC groupVentral striatum/Healthy control participantsTotal IGT scoreAnterior cingulate regionsGambling TaskNeural processesNeural processingTask performance
2012
Diminished Frontostriatal Activity During Processing of Monetary Rewards and Losses in Pathological Gambling
Balodis IM, Kober H, Worhunsky PD, Stevens MC, Pearlson GD, Potenza MN. Diminished Frontostriatal Activity During Processing of Monetary Rewards and Losses in Pathological Gambling. Biological Psychiatry 2012, 71: 749-757. PMID: 22336565, PMCID: PMC3460522, DOI: 10.1016/j.biopsych.2012.01.006.Peer-Reviewed Original ResearchConceptsAlcohol dependencePathological gamblingVentral striatumMagnetic resonance imaging studyResonance imaging studyFunctional magnetic resonance imaging studyBrain activation changesMonetary incentive delay taskReward processingLoss processingPresent functional magnetic resonance imaging (fMRI) studyControl comparison groupIncentive delay taskVentral striatal activationPG groupMonetary rewardsVentromedial prefrontal cortexSimilar associationImaging studiesFrontostriatal activityLoss anticipationConsistent alterationsActivation changesPrefrontal cortexLevels of impulsivity