2021
Longitudinal Effects of Acute Cannabis Exposure on Automobile Driving Behavior in a Naturalistic Simulated Environment
Meda S, Boer E, Ward N, Book G, Stevens M, Boyle C, Mubeen M, Pearlson G. Longitudinal Effects of Acute Cannabis Exposure on Automobile Driving Behavior in a Naturalistic Simulated Environment. 2021 DOI: 10.26828/cannabis.2021.01.000.21.Peer-Reviewed Original ResearchAcute cannabis exposureHigh-dose subjectsDrug dose levelsSignificant public health riskCannabis exposureDose studyDrug exposureSimulated environmentInfluence of cannabisSafe overtakingSingle acuteHigh doseSPSS v24Psychomotor functionComplex dayDriving functionsDose levelsHigh dosesSeparate daysPublic health riskOverall riskIntoxicated subjectsDoseThree timesNumerous metrics
2012
Memantine, an NMDA receptor antagonist, differentially influences Go/No-Go performance and fMRI activity in individuals with and without a family history of alcoholism
Jamadar S, DeVito EE, Jiantonio RE, Meda SA, Stevens MC, Potenza MN, Krystal JH, Pearlson GD. Memantine, an NMDA receptor antagonist, differentially influences Go/No-Go performance and fMRI activity in individuals with and without a family history of alcoholism. Psychopharmacology 2012, 222: 129-140. PMID: 22311382, PMCID: PMC3674025, DOI: 10.1007/s00213-011-2628-2.Peer-Reviewed Original ResearchConceptsNMDA receptor antagonistFamily historyFHN subjectsReceptor antagonistFHP subjectsN-methyl-D-aspartate receptor functionReceptor functionIdentical-appearing placeboEffects of memantineFMRI activityNMDA receptor functionCorrect rejectsSingle doseMemantineGo/No-Go taskSeparate daysTemporal regionsCingulate activation