2024
Changes in hoarding-related beliefs and associated neural changes during a simulated discarding task after cognitive-behavioral treatment for hoarding disorder
Knowles K, Stevens M, Levy H, Tolin D. Changes in hoarding-related beliefs and associated neural changes during a simulated discarding task after cognitive-behavioral treatment for hoarding disorder. Journal Of Psychiatric Research 2024, 180: 473-481. PMID: 39547046, PMCID: PMC11606758, DOI: 10.1016/j.jpsychires.2024.11.017.Peer-Reviewed Original ResearchCognitive-behavioral therapyHoarding-related beliefsFunctional magnetic resonance imagingHoarding disorderNeural activityMaladaptive beliefsCourse of CBTGroup cognitive-behavioral therapyLeft anterior cingulate cortexLeft middle frontal gyrusAssociated with cognitive changesCognitive-behavioral treatmentAssociated with increased activityAnterior ventral insulaAnterior cingulate cortexMiddle frontal gyrusInferior temporal lobeLeft middle insulaCognitive-behavioralAssociated with specific changesFrontal gyrusCingulate cortexMiddle insulaNeural regionsVentral insula
2018
Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA Consortium
Kong XZ, Mathias SR, Guadalupe T, Glahn D, Franke B, Crivello F, Tzourio-Mazoyer N, Fisher S, Thompson P, Francks C, Kong X, Mathias S, Guadalupe T, Abé C, Agartz I, Akudjedu T, Aleman A, Alhusaini S, Allen N, Ames D, Andreassen O, Vasquez A, Armstrong N, Bergo F, Bastin M, Batalla A, Bauer J, Baune B, Baur-Streubel R, Biederman J, Blaine S, Boedhoe P, Bøen E, Bose A, Bralten J, Brandeis D, Brem S, Brodaty H, Yüksel D, Brooks S, Buitelaar J, Bürger C, Bülow R, Calhoun V, Calvo A, Canales-Rodríguez E, Canive J, Cannon D, Caparelli E, Castellanos F, Cavalleri G, Cendes F, Chaim-Avancini T, Chantiluke K, Chen Q, Chen X, Cheng Y, Christakou A, Clark V, Coghill D, Connolly C, Conzelmann A, Córdova-Palomera A, Cousijn J, Crow T, Cubillo A, Dale A, Dannlowski U, Ambrosino de Bruttopilo S, de Zeeuw P, Deary I, Delanty N, Demeter D, Di Martino A, Dickie E, Dietsche B, Doan N, Doherty C, Doyle A, Durston S, Earl E, Ehrlich S, Ekman C, Elvsåshagen T, Epstein J, Fair D, Faraone S, Fernández G, Filho G, Förster K, Fouche J, Foxe J, Frodl T, Fuentes-Claramonte P, Fullerton J, Garavan H, Garcia D, Gotlib I, Goudriaan A, Grabe H, Groenewold N, Grotegerd D, Gruber O, Gurholt T, Haavik J, Hahn T, Hansell N, Harris M, Hartman C, Hernández M, Heslenfeld D, Hester R, Hibar D, Ho B, Ho T, Hoekstra P, van Holst R, Hoogman M, Høvik M, Howells F, Hugdahl K, Huyser C, Ingvar M, Irwin L, Ishikawa A, James A, Jahanshad N, Jernigan T, Jönsson E, Kähler C, Kaleda V, Kelly C, Kerich M, Keshavan M, Khadka S, Kircher T, Kohls G, Konrad K, Korucuoglu O, Krämer B, Krug A, Kwon J, Lambregts-Rommelse N, Landén M, Lázaro L, Lebedeva I, Lenroot R, Lesch K, Li Q, Lim K, Liu J, Lochner C, London E, Lonning V, Lorenzetti V, Luciano M, Luijten M, Lundervold A, Mackey S, MacMaster F, Maingault S, Malpas C, Malt U, Mataix-Cols D, Martin-Santos R, Mayer A, McCarthy H, Mitchell P, Mueller B, Maniega S, Mazoyer B, McDonald C, McLellan Q, McMahon K, McPhilemy G, Momenan R, Morales A, Narayanaswamy J, Moreira J, Nerland S, Nestor L, Newman E, Nigg J, Nordvik J, Novotny S, Weiss E, O’Gorman R, Oosterlaan J, Oranje B, Orr C, Overs B, Pauli P, Paulus M, Plessen K, von Polier G, Pomarol-Clotet E, Portella M, Qiu J, Radua J, Ramos-Quiroga J, Reddy Y, Reif A, Roberts G, Rosa P, Rubia K, Sacchet M, Sachdev P, Salvador R, Schmaal L, Schulte-Rüther M, Schweren L, Seidman L, Seitz J, Serpa M, Shaw P, Shumskaya E, Silk T, Simmons A, Simulionyte E, Sinha R, Sjoerds Z, Smelror R, Soliva J, Solowij N, Souza-Duran F, Sponheim S, Stein D, Stein E, Stevens M, Strike L, Sudre G, Sui J, Tamm L, Temmingh H, Thoma R, Tomyshev A, Tronchin G, Turner J, Uhlmann A, van Erp T, van den Heuvel O, van der Meer D, van Eijk L, Vance A, Veer I, Veltman D, Venkatasubramanian G, Vilarroya O, Vives-Gilabert Y, Voineskos A, Völzke H, Vuletic D, Walitza S, Walter H, Walton E, Wardlaw J, Wen W, Westlye L, Whelan C, White T, Wiers R, Wright M, Wittfeld K, Yang T, Yasuda C, Yoncheva Y, Yücel M, Yun J, Zanetti M, Zhen Z, Zhu X, Ziegler G, Zierhut K, de Zubicaray G, Zwiers M, Glahn D, Franke B, Crivello F, Tzourio-Mazoyer N, Fisher S, Thompson P, Francks C, Farde L, Flyckt L, Engberg G, Erhardt S, Fatouros-Bergman H, Cervenka S, Schwieler L, Piehl F, Agartz I, Collste K, Victorsson P, Malmqvist A, Hedberg M, Orhan F. Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA Consortium. Proceedings Of The National Academy Of Sciences Of The United States Of America 2018, 115: e5154-e5163. PMID: 29764998, PMCID: PMC5984496, DOI: 10.1073/pnas.1718418115.Peer-Reviewed Original ResearchConceptsBrain asymmetryCortical thicknessHealthy individualsAltered brain asymmetryCerebral cortical asymmetryENIGMA consortiumTransverse temporal gyrusPopulation-level asymmetriesInferior frontal gyrusPsychiatric disordersMRI scansParahippocampal gyrusCardinal featuresSignificant associationIntracranial volumeNeuropsychiatric disordersTemporal gyrusThicker cortexFrontal gyrusCortical asymmetryHuman brain organizationLeft hemisphereGyrusLateralized functionsBrain organization
2013
A pilot study linking reduced fronto–Striatal recruitment during reward processing to persistent bingeing following treatment for binge‐eating disorder
Balodis IM, Grilo CM, Kober H, Worhunsky PD, White MA, Stevens MC, Pearlson GD, Potenza MN. A pilot study linking reduced fronto–Striatal recruitment during reward processing to persistent bingeing following treatment for binge‐eating disorder. International Journal Of Eating Disorders 2013, 47: 376-384. PMID: 24729034, PMCID: PMC3986812, DOI: 10.1002/eat.22204.Peer-Reviewed Original ResearchConceptsBinge-eating disorderFunctional magnetic resonance imagingReward processingMonetary incentive delay taskInferior frontal gyrusIncentive delay taskBinge-eating statusMedial prefrontal cortexBrain reward circuitryNeural correlatesDelay taskSpecific brain regionsFrontal gyrusNeurobiological underpinningsOutcome phasePrefrontal cortexReward circuitryVentral striatumAnticipatory phaseBrain regionsTreatment outcomesDiminished recruitmentProcessingMagnetic resonance imagingIndividualsA large scale (N=102) functional neuroimaging study of response inhibition in a Go/NoGo task
Steele VR, Aharoni E, Munro GE, Calhoun VD, Nyalakanti P, Stevens MC, Pearlson G, Kiehl KA. A large scale (N=102) functional neuroimaging study of response inhibition in a Go/NoGo task. Behavioural Brain Research 2013, 256: 529-536. PMID: 23756137, PMCID: PMC4437665, DOI: 10.1016/j.bbr.2013.06.001.Peer-Reviewed Original ResearchConceptsSuccessful response inhibitionGo/NoGo taskResponse inhibitionUnsuccessful response inhibitionMagnetic resonance imaging studySupplementary motor areaResonance imaging studyFunctional magnetic resonance imaging studyInferior parietal lobuleNoGo taskInferior prefrontal regionsHealthy adult participantsBasal gangliaInferior frontal gyrusHemodynamic responseMotor areaAnterior cingulateImaging studiesParietal lobuleFronto-parietal networkHemodynamic activityFrontal gyrusFrontostriatal regionsSmall sample studiesPrefrontal regions
2012
Neural mechanisms of cognitive behavioral therapy response in Hoarding Disorder: A pilot study
Tolin D, Stevens M, Nave A, Villavicencio A, Morrison S. Neural mechanisms of cognitive behavioral therapy response in Hoarding Disorder: A pilot study. Journal Of Obsessive-Compulsive And Related Disorders 2012, 1: 180-188. DOI: 10.1016/j.jocrd.2012.04.001.Peer-Reviewed Original ResearchCognitive behavioral therapyMedial frontal gyrusFrontal gyrusHemodynamic activityManualized group cognitive behavioral therapyCognitive behavioral therapy responsePosterior cingulateFunctional magnetic resonance imaging (fMRI) taskGroup cognitive behavioral therapyRight superior temporal gyrusDecision-making taskInsula/putamenRight posterior hippocampusSuperior temporal gyrusHealthy control participantsParietal lobe regionsHippocampus/parahippocampusNeural functionHoarding DisorderNeural mechanismsBehavioral therapyTemporal gyrusPosterior hippocampusHC participantsLobe regions
2011
An Initial Study of Neural Responses to Monetary Incentives as Related to Treatment Outcome in Cocaine Dependence
Jia Z, Worhunsky PD, Carroll KM, Rounsaville BJ, Stevens MC, Pearlson GD, Potenza MN. An Initial Study of Neural Responses to Monetary Incentives as Related to Treatment Outcome in Cocaine Dependence. Biological Psychiatry 2011, 70: 553-560. PMID: 21704307, PMCID: PMC3162064, DOI: 10.1016/j.biopsych.2011.05.008.Peer-Reviewed Original ResearchConceptsRight ventral striatumVentral striatumCocaine dependenceRight insulaMonetary incentive delay taskRight caudateReward-based decisionIncentive delay taskTreatment retentionFunctional magnetic resonanceCD participantsMedial frontal gyrusRight thalamusUrine toxicologyTreatment outcomesReward anticipationReward processingDelay taskTask performanceFrontal gyrusGreater activationNeural responsesRewarding outcomesRight subcallosal gyrusMonetary rewards