2013
Error processing in current and former cocaine users
Castelluccio BC, Meda SA, Muska CE, Stevens MC, Pearlson GD. Error processing in current and former cocaine users. Brain Imaging And Behavior 2013, 8: 87-96. PMID: 23949893, PMCID: PMC3925762, DOI: 10.1007/s11682-013-9247-y.Peer-Reviewed Original ResearchConceptsFormer cocaine usersError processingSupramarginal gyrusCocaine usersBOLD responseRight inferior parietal lobuleAspects of impulsivityAbstinent cocaine usersCocaine abuse/dependenceInferior parietal lobuleCocaine-dependent individualsCurrent cocaine usersCognitive compensationNeural differencesPrepotent responsesResponse inhibitionAbuse/dependenceCorrect rejectionsSpecific deficitsBOLD activityTrait measuresMaladaptive behaviorsParietal lobuleAddictive behaviorsNeural activityRobust Changes in Reward Circuitry During Reward Loss in Current and Former Cocaine Users During Performance of a Monetary Incentive Delay Task
Patel KT, Stevens MC, Meda SA, Muska C, Thomas AD, Potenza MN, Pearlson GD. Robust Changes in Reward Circuitry During Reward Loss in Current and Former Cocaine Users During Performance of a Monetary Incentive Delay Task. Biological Psychiatry 2013, 74: 529-537. PMID: 23778289, PMCID: PMC3775945, DOI: 10.1016/j.biopsych.2013.04.029.Peer-Reviewed Original ResearchConceptsMonetary incentive delay taskVentral tegmental areaHealthy subjectsFormer cocaine usersLoss anticipationIncentive delay taskCocaine usersTegmental areaLoss outcomesCurrent cocaine usersDrug useAbnormal brain activation patternsCocaine addictionCurrent usersActivation patternsCocaine-using groupDelay taskLong-term cocaine abstinenceFunctional magnetic resonanceSubstance-induced alterationsBrain activation patternsCircuit abnormalitiesAnterior cingulate activationControl subjectsRisk factors
2009
Investigating the behavioral and self-report constructs of impulsivity domains using principal component analysis
Meda SA, Stevens MC, Potenza MN, Pittman B, Gueorguieva R, Andrews MM, Thomas AD, Muska C, Hylton JL, Pearlson GD. Investigating the behavioral and self-report constructs of impulsivity domains using principal component analysis. Behavioural Pharmacology 2009, 20: 390-399. PMID: 19724194, PMCID: PMC3268653, DOI: 10.1097/fbp.0b013e32833113a3.Peer-Reviewed Original ResearchConceptsSelf-report measuresImpulsivity domainsImpulsivity constructsSelf-reported impulsivityDistinct neural systemsAspects of impulsivitySelf-report constructsSelf-reported compulsivityMeasures of impulsivityReward/punishmentConstruct of impulsivitySupplementary goalCurrent cocaine usersTemporal discountingFive-factor solutionLaboratory tasksMaladaptive behaviorsDifferent domainsImpulsivityMultidimensional constructBehavioral activationNeural systemsHuman behaviorBehavioral studiesSupplemental analyses